Protein Alignment CG33127 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_787956.1
• Gene: CG33127 / 318893
• FlyBaseID: FBgn0053127
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 80/266 - (30%)
• Similarity: 117/266 - (43%)
• Gaps: 31/266 - (11%)

  Fly    24 HLTLRDTEQVHAEIQPLIIDGYDVQGVDNVPYLVSLSLTRATYTHLCGASIIGKRWLLTAAHCVD 88
            |..|.|.....|.:..::  |....|....|:.|||.|.|.  .|.|||.::.:||||:||||.|
Human   845 HTQLPDCGLAPAALTRIV--GGSAAGRGEWPWQVSLWLRRR--EHRCGAVLVAERWLLSAAHCFD 905

  Fly    89 ELRTFNGDA------VGTPVYAGIINRSNVTAAQVRYVDFASTHRSFNGNAGSDNIALLHVSESF 147
                ..||.      :|||..:|       ...|:..|.....|..:|......::|||.::...
Human   906 ----VYGDPKQWAAFLGTPFLSG-------AEGQLERVARIYKHPFYNLYTLDYDVALLELAGPV 959

  Fly   148 EYNARVQQIALPDINDDYSNKTAAAY-GWGLTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAP 211
            ..:..|:.|.||:......:.|.... ||| :..:|...:::||.|...||:...|:...|..
Human   960 RRSRLVRPICLPEPAPRPPDGTRCVITGWG-SVREGGSMARQLQKAAVRLLSEQTCRRFYPVQ-- 1021

  Fly   212 LTAQQVCS-----QVKTCYGDGGTPLIYWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIG 271
            ::::.:|:     .|.:|.||.|.||.....:|...|.|:.||.| .||..:.|.|||.|....|
Human  1022 ISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGY-GCGRPHFPGVYTRVAAVRG 1085

  Fly   272 WIHQTI 277
            ||.|.|
Human  1086 WIGQHI 1091

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	72/243 (30%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113
		Pneumo_att_G	<717..>867	CDD:114270	5/23 (22%)
		Tryp_SPc	861..1087	CDD:238113	72/244 (30%)