DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33127 and tmprss6

DIOPT Version :9

Sequence 1:	NP_787956.1	Gene:	CG33127 / 318893	FlyBaseID:	FBgn0053127	Length:	284	Species:	Drosophila melanogaster
Sequence 2:	XP_004913946.2	Gene:	tmprss6 / 100489045	XenbaseID:	XB-GENE-1011573	Length:	806	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	58/246 - (23%)
Similarity:	96/246 - (39%)	Gaps:	53/246 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PYLVSLSLTRATYTHLCGASIIGKRWLLTAAHCVDELRTFNGDAVGTP----VYAGIINRSNVTA 114
            |:..||.:..   .|:||.:::..:|:||||||      |..::..:|    ||.|.:..|..|.
Frog   583 PWQASLQVRG---EHICGGTLVADQWILTAAHC------FTPESYASPEVWTVYLGKVRLSRSTQ 638

  Fly   115 AQVRY-VDFASTHRSFNGNAGSDNIALLHVSESFEYNA-RVQQIALPDINDDY-SNKTAAAYGWG 176
            .::.: |.....|..::.::...::||:.:.......: .||.|.||.....: :..:....|||
Frog   639 KELAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLTSPHVQPICLPSSTHHFPTGSSCWVTGWG 703

  Fly   177 LTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAPLTAQQVCSQV-------------------K 222
            ....:|.. |..||                ..|..|.||.:|:::                   .
Frog   704 SVKENGPT-SDVLQ----------------KVDIQLVAQDICTELYRYQISPRMLCAGYRDGSKD 751

  Fly   223 TCYGDGGTPLIYWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIGWI 273
            .|.||.|:||:....:|.....||.||. ..||......||:.:...:.||
Frog   752 ACQGDSGSPLVCKTASGRWFQAGLVSWG-AGCGIPRYFGVYSRITRLVQWI 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33127	NP_787956.1	Tryp_SPc	41..276	CDD:238113	58/246 (24%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	56/244 (23%)
tmprss6	XP_004913946.2	SEA	77..176	CDD:396113
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060
		Tryp_SPc	572..804	CDD:238113	58/246 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010