Protein Alignment CG33124 and Slc5a7

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_445973.2
• Gene: Slc5a7 / 85426
• RGDID: 69270
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 629
• Identity: 126/629 - (20%)
• Similarity: 228/629 - (36%)
• Gaps: 183/629 - (29%)

  Fly    19 ILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGS--KKMNEYLMGSGHLKVFPVAMSLIASF 81
            :|...:|::..|  |||                |.|:  ::....::|...:.:.....::.|::
  Rat    16 LLIFLVGIWAAW--KTK----------------NSGNAEERSEAIIVGGRDIGLLVGGFTMTATW 62

  Fly    82 ISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRS-SYEYLGMRFHPLIRN 145
            :.|..|.|....:|..|...:.....|   |.::|.|...:|.|..:|| .|
  Rat    63 VGGGYINGTAEAVYGPGCGLAWAQAPI---GYSLSLILGGLFFAKPMRSKGY------------- 111

  Fly   146 IVSIMFVIEVLLYTPF----------VVFVPAL--------ALNQASGLNIHMI-----EVLIIV 187
                     |.:..||          ::|:|||        |:..|.|..|.:|     .:.:||
  Rat   112 ---------VTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIV 167

  Fly   188 ---VCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCY--ITDLDDFFESLVDGGRLIFGN 247
               :.::|||:|||.:|.:||:.|:..:|..:.:....|..:  :||:         |...:...
  Rat   168 SALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDI---------GFTAVHAK 223

  Fly   248 INPSPYVRNTVWSV------------VIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFV 300
            .. ||:: .|:.|:            ::|| ..|       |....|.:|
  Rat   224 YQ-SPWL-GTIESIEVYTWLDNFLLLMLGG-IPW-------QAYFQRVLS--------------- 263

  Fly   301 LGSIIFYSVLSFL---GLLIFNMYKDC------------------DPLSAGQIMNNDQLVPLFVV 344
            ..|..:..|||||   |.|:..:...|                  ||.:..:.   |.::|: |:
  Rat   264 SSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGFPDPKTKEEA---DMILPI-VL 324

  Fly   345 QSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIM 409
            |.:..:| |....:..:..|.:||....:.|.|.:..::|.:..|:....:.....:::.|:.:.
  Rat   325 QYLCPVY-ISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVF 388

  Fly   410 GALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLLTGWIT 474
            ||......||.:.|.|:..:...||.|.      ||...:.|.:.....| .|.:||::
  Rat   389 GASATAMALLTKTVYGLWYLSSDLVYII------IFPQLLCVLFIKGTNT-YGAVAGYI------ 440

  Fly   475 FGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTVVVVGS 539
            ||..:....|:.:.:..|  :...||....:..::   .|.||...||.    .....|.:.|..
  Rat   441 FGLFLRITGGEPYLYLQP--LIFYPGYYPDKNGIY---NQRFPFKTLSM----VTSFFTNICVSY 496

  Fly   540 LVSLV----TKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKS 579
            |...:    |.|..:     |:...|:.|      ..:.|:||:
  Rat   497 LAKYLFESGTLPPKL-----DIFDAVVSR------HSEENMDKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	115/577 (20%)
Slc5a7	NP_445973.2	SLC5sbd_CHT	8..495	CDD:271368	116/582 (20%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000269|PubMed:17092608	502..580		8/39 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830