Protein Alignment CG33124 and SLC5A5

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_011526494.1
• Gene: SLC5A5 / 6528
• HGNCID: 11040
• Length: 654
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 170/591 - (28%)
• Similarity: 281/591 - (47%)
• Gaps: 66/591 - (11%)

  Fly     6 FGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKV 70
            ||..||.||..:.::|..|||:.|                    :...|.:...::..|...|..
Human    12 FGAWDYGVFALMLLVSTGIGLWVG--------------------LARGGQRSAEDFFTGGRRLAA 56

  Fly    71 FPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYL 135
            .||.:||.|||:|.|.:||.|||.|.||.::..:.|..::..:..:.:::|||..|.:.|:||||
Human    57 LPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYL 121

  Fly   136 GMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKA 200
            .|||...:|...::.:::..:|||..|::.|||.|||.:||:|....:...::|..||.:||:||
Human   122 EMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKA 186

  Fly   201 VVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVWSVVIGG 265
            ||.||::|||:|.:...||.......:...........:..|:...:.||.|..|.|.|:.|:||
Human   187 VVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGG 251

  Fly   266 AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAG 330
            ...|.|:..|:|..|.||::....|.|:.::....:|..:..|..:..|:::|..|.|||||..|
Human   252 TLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLG 316

  Fly   331 QIMNNDQL-----------VPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDI 384
            :|...|||           :||.|:.....:.|:||||:|..:...||:.|..:|:.:.|.::|:
Human   317 RISAPDQLSGRLTPSSPQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDL 381

  Fly   385 VRGCFKMQPGETASAIIVKATIVIMG-ALVFGEVLLLEKV------SGILSICMSLVAIATSSTF 442
            ::...:       |....|..|:..| :|::|...|....      .|:|....:::.:.:....
Human   382 IKPRLR-------SLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLL 439

  Fly   443 GIFTLAVLVPWANTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASC--------- 498
            |.|.|.:.:|..||.|...|..||..|:.|:..|:.:...|.|. ...||.|.|.|
Human   440 GAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQT-MRVLPSSAARCVALSVNASG 503

  Fly   499 -------PGNVTAR-ENVWVDEEQ---VFPLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKS 552
                   |.|.::| .:..:|..:   ....:.:|:.:...:|.||.|:.|:|:|.:|.||...:
Human   504 LLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRST 568

  Fly   553 LDSDLI 558
            |...|:
Human   569 LAPGLL 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	157/561 (28%)
SLC5A5	XP_011526494.1	SLC5sbd_NIS	15..565	CDD:271393	165/577 (29%)