Protein Alignment CG33124 and SLC5A3

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 124/613 - (20%)
• Similarity: 231/613 - (37%)
• Gaps: 157/613 - (25%)

  Fly     8 TVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFP 72
            |.|..:.....||.:.||.:..|  |:.:...|.                   |.:....:....
Human     7 TADIAIVALYFILVMCIGFFAMW--KSNRSTVSG-------------------YFLAGRSMTWVA 50

  Fly    73 VAMSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSY 132
            :..||..|.|.     |:|..|..|.......:::.::|..::     .::::|::....|.:..
Human    51 IGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLL-----GWVFIPIYIRSGVYTMP 110

  Fly   133 EYLGMRF--HPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLL 195
            |||..||  |.:.....::..::.:.......::..||.:.::.|.|:::..:|:|.:..:.|:.
Human   111 EYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVT 175

  Fly   196 GGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------------SLVDGGRLIFG- 246
            |||.||::||..|.::|....:.:.|::   |.::..|.|             |::    |.:.
Human   176 GGLVAVIYTDTLQALLMIIGALTLMIIS---IMEIGGFEEVKRRYMLASPDVTSIL----LTYNL 233

  Fly   247 ------NINP---------SPYVRNTVWSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKM 291
                  |::|         :|...:..|...|.|     .:||    ...|.:|.|.::..|:..
Human   234 SNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYW----CADQVIVQRVLAAKNIAH 294

  Fly   292 AR--TSIAFF-------------VLGSIIFYSVLSFLG----LLIFNMYKDCDPLSAGQIMNNDQ 337
            |:  |.:|.|             ::..|:|...::.:.    :|:......|..::..:::.  :
Human   295 AKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVM--K 357

  Fly   338 LVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDI---VRGCFKMQPGETASA 399
            |||:          |:.||.:|.:..|.:|.|....||.|.:...|:   :|.....:.......
Human   358 LVPV----------GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGR 412

  Fly   400 IIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVA-IATSSTFGIFTLAVLVPWANTVGTAVGG 463
            |.|...:||..|.|   .:::|...|.:.:.:..|| ..|.....:|.||:.....|..|...||
Human   413 IFVAFMVVISIAWV---PIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGG 474

  Fly   464 IAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFH---- 524
            :|||:| |.:......|        :|.|    .|            |:....|.|....|
Human   475 MAGFVL-GAVRLILAFA--------YRAP----EC------------DQPDNRPGFIKDIHYMYV 514

  Fly   525 -----WINPIGALTVVVVGSLVSLVTKP 547
                 |:.  |.:||:     |||:|.|
Human   515 ATGLFWVT--GLITVI-----VSLLTPP 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	116/596 (19%)
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	123/611 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146450
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750