Protein Alignment CG33124 and SLC5A7

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001291934.1
• Gene: SLC5A7 / 60482
• HGNCID: 14025
• Length: 580
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 125/633 - (19%)
• Similarity: 233/633 - (36%)
• Gaps: 170/633 - (26%)

  Fly     7 GTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGS--KKMNEYLMGSGHLK 69
            |.:...||.   :|.:.:|::..|  :||                |.||  ::....::|...:.
Human     7 GLIAIIVFY---LLILLVGIWAAW--RTK----------------NSGSAEERSEAIIVGGRDIG 50

  Fly    70 VFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRS-SYE 133
            :.....::.|:::.|..|.|....:|..|  |.|......| |.::|.|...:|.|..:|| .|
Human    51 LLVGGFTMTATWVGGGYINGTAEAVYVPG--YGLAWAQAPI-GYSLSLILGGLFFAKPMRSKGY- 111

  Fly   134 YLGMRFHPLIRNIVSIMFVIEVLLYTPF----------VVFVPAL--------ALNQASG----- 175
                                 |.:..||          ::|:|||        |:..|.|
Human   112 ---------------------VTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISV 155

  Fly   176 ---LNIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESL 237
               :::|:..::..::..:|||:|||.:|.:||:.|:..:|..:.:....|..:....|..|.::
Human   156 IIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAV 220

  Fly   238 -----------VDGGR----------LIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVH 281
                       ||...          |:.|.|....|.:..:           :|.:|.:..::.
Human   221 HAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVL-----------SSSSATYAQVLS 274

  Fly   282 RYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAGQIMNNDQLVPLFVVQS 346
            ...:...|.||..:|....:|:...::..:: ||        .||.:..:.   |.::|: |:|.
Human   275 FLAAFGCLVMAIPAILIGAIGASTDWNQTAY-GL--------PDPKTTEEA---DMILPI-VLQY 326

  Fly   347 VGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGA 411
            :..:| |....:..:..|.:||....:.|.|.:..::|.:..|:....:.....:::.|:.:.||
Human   327 LCPVY-ISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGA 390

  Fly   412 LVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLL--TGWIT 474
            ......||.:.|.|:..:...||.|.   .|......:.|...||.|...|.::|..|  ||
Human   391 SATAMALLTKTVYGLWYLSSDLVYIV---IFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITG--- 449

  Fly   475 FGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRL----SFHWINPIGALTVV 535
                     |:.:.:..|  :...||.......::   .|.||...|    ||        ||.:
Human   450 ---------GEPYLYLQP--LIFYPGYYPDDNGIY---NQKFPFKTLAMVTSF--------LTNI 492

  Fly   536 VVGSLVSLV----TKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKS 579
            .:..|...:    |.|..:     |:...|:.|      ..:.|:||:
Human   493 CISYLAKYLFESGTLPPKL-----DVFDAVVAR------HSEENMDKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	113/579 (20%)
SLC5A7	NP_001291934.1	SLC5sbd_CHT	8..495	CDD:271368	115/585 (20%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		8/39 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146446
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740