Protein Alignment CG33124 and Slc5a3

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_059087.2
• Gene: Slc5a3 / 53881
• MGIID: 1858226
• Length: 718
• Species: Mus musculus
• Alignment Length: 592
• Identity: 118/592 - (19%)
• Similarity: 225/592 - (38%)
• Gaps: 137/592 - (23%)

  Fly    19 ILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVAMSLIASFIS 83
            ||.:.||.:..|  |:.:...|.                   |.:....:....:..||..|.|.
Mouse    18 ILVMCIGFFAMW--KSNRSTVSG-------------------YFLAGRSMTWVAIGASLFVSNIG 61

  Fly    84 -----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYLGMRF--HP 141
                 |:|..|..|.......:::.::|..::     .::::|::....|.:..|||..||  |.
Mouse    62 SEHFIGLAGSGAASGFAVGAWEFNALLLLQLL-----GWVFIPIYIRSGVYTMPEYLSKRFGGHR 121

  Fly   142 LIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKAVVHTDI 206
            :.....::..::.:.......::..||.:.::.|.|:::..:|:|.:..:.|:.|||.||::||.
Mouse   122 IQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDT 186

  Fly   207 WQVVIMFASVVVVAILATCYITDLDD----FFESLVDGGRLI----FGNINP------------- 250
            .|.::|....:.:.:::...|...::    :..:..|...::    ..|.|.
Mouse   187 LQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMVHPKANALKML 251

  Fly   251 -SPYVRNTVWSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMAR--TSIAFF-------- 299
             .|...:..|...|.|     .:||    ...|.:|.|.::..|:..|:  |.:|.|
Mouse   252 RDPTDEDVPWPGFILGQTPASVWYW----CADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFI 312

  Fly   300 -----VLGSIIFYSVLSFLG----LLIFNMYKDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPG 355
                 ::..|:|...::.:.    :.:......|..::..:::..  |||:          |:.|
Mouse   313 IVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMT--LVPV----------GLRG 365

  Fly   356 LFIAGIFGAGLSSLSVFLNSTSLVILQDI---VRGCFKMQPGETASAIIVKATIVIMGALVFGEV 417
            |.:|.:..|.:|.|....||.|.:...|:   :|.....:.......|.|...:||..|.|   .
Mouse   366 LMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWV---P 427

  Fly   418 LLLEKVSGILSICMSLVA-IATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLLTGWITFGSQIAA 481
            :::|...|.:.:.:..|| ..|.....:|.||:.....|..|...||:|||:| |.:..   |.|
Mouse   428 IIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL-GAVRL---ILA 488

  Fly   482 ASGQLHHHRLPVSVASC------PGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTVVVVGSL 540
            .:     :|.|    .|      ||.:.....::|         ..:..||.  |.:||:
Mouse   489 FT-----YRAP----ECDQPDNRPGFIKDIHYMYV---------ATALFWIT--GLITVI----- 528

  Fly   541 VSLVTKP 547
            |||:|.|
Mouse   529 VSLLTPP 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	111/576 (19%)
Slc5a3	NP_059087.2	SLC5sbd_SMIT	9..718	CDD:271382	118/592 (20%)