DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33124 and CG42235

DIOPT Version :9

Sequence 1:	NP_001097056.3	Gene:	CG33124 / 318891	FlyBaseID:	FBgn0053124	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_651446.2	Gene:	CG42235 / 43136	FlyBaseID:	FBgn0250757	Length:	698	Species:	Drosophila melanogaster

Alignment Length:	594	Identity:	200/594 - (33%)
Similarity:	323/594 - (54%)	Gaps:	24/594 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEME------SSPADTPEISIPNFGSKKMNEYLMG 64
            ||.|||.||:.:..:...||.|||:|:|.:|:.:      ...|...|    ..||:.: :||:|
  Fly   102 FGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEE----RRGSEAL-DYLVG 161

  Fly    65 SGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVR 129
            ...:||||||:||:|||:||:::||..:|||.|||||:.|::.:.|.|....||:||||..||:.
  Fly   162 GRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLT 226

  Fly   130 SSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTL 194
            |:|||...||...:|...|.:||:..:|:.|..::||||.|||.||:::..|..:...:|::||.
  Fly   227 STYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTS 291

  Fly   195 LGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVW 259
            :||:|.||.||:.|..:|..|:::|.|..|..:..|....:......||:..::...|..|..|:
  Fly   292 VGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGVF 356

  Fly   260 SVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDC 324
            ::.:|||.:......::|.:|.||::|||.|..:.::...::|.:....:..::|||.|..:..|
  Fly   357 ALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLLAFAEFYHC 421

  Fly   325 DPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCF 389
            ||::.|.....||::||:||::||||.|:.|||:||:|.|.|||||..|||.|.|||.|.|....
  Fly   422 DPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFR 486

  Fly   390 KMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWA 454
            |....|..:|.:::..::..|.:....|.:::::..::.:..::.||......|.|::.:|:|:.
  Fly   487 KKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFV 551

  Fly   455 NTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASC------PGNVTARENVWVDEE 513
            .|.....|.......|.:|...:|||..:|.|.....|||:..|      |.|..|.......|.
  Fly   552 KTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTATPTES 616

  Fly   514 QVFPLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRF-------LPKECF 571
            ....:..:||.|...:|::..|:...|.:|.....|.:.:|.:|||||:.:|       :..|..
  Fly   617 TSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVASEEK 681

  Fly   572 KQRNLDKSE 580
            ...||.:||
  Fly   682 NNFNLHESE 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	182/535 (34%)
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	184/545 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448248
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D32058at33392
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900