Protein Alignment CG33124 and Slc5a12

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001102058.1
• Gene: Slc5a12 / 362188
• RGDID: 1311652
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 180/571 - (31%)
• Similarity: 294/571 - (51%)
• Gaps: 33/571 - (5%)

  Fly     6 FGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKV 70
            |...||.||..:.::|..||::|. ||:.||...                   .|:|:|...:..
  Rat     6 FEAWDYVVFAALFVISSGIGVFFA-IKERKKTTS-------------------REFLVGGRQMSF 50

  Fly    71 FPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYL 135
            .|||:||.|||:|.|.:||.|:|:|.:|..:.:.:::........|.::||||....:.|:||||
  Rat    51 APVALSLTASFMSAVTVLGTPAEVYRFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYL 115

  Fly   136 GMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKA 200
            .:||:..:|...:|:::::.:|||..||:.|||||||.:|.|:........:||..|..||||||
  Rat   116 QLRFNKPVRYAATIIYILQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKA 180

  Fly   201 VVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVWSVVIGG 265
            ||.||.:|:|:|....:.|.|..:.::...|:..|...:|.||...:.:..|..|:|.|::.:||
  Rat   181 VVWTDAFQMVVMIVGFLTVLIQGSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGG 245

  Fly   266 AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAG 330
            .|.|..|..|:|:.:.|.:|....|.|:.::.|.:||..|......|.||:::..||||||.::|
  Rat   246 TFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSG 310

  Fly   331 QIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGE 395
            .|:..|||:|.||::....:.|:||||:|..|...||:::..:|:.:.|..:|.|:.||. ...:
  Rat   311 AILAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFP-HLSD 374

  Fly   396 TASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTA 460
            |.|..|.|...::.|.:.....:|...:..::...:|:..:......|:|||.::.|:.|..|..
  Rat   375 TLSTWISKGLCLLFGIICTSMAVLASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGAL 439

  Fly   461 VGGIAGFLLTGWITFGSQI--AAASGQLHHHRLPVSVASC-PGNVTARENVWVDEEQVF--PLFR 520
            .|.:.|..|:.|:..|:.:  |..|..|   .||:|...| ..|.|..|...:....|.  ..:.
  Rat   440 GGLLTGITLSFWVGIGAFVYPAPDSKTL---PLPLSTEFCVQQNKTTTEAYQLSSRPVLADTWYS 501

  Fly   521 LSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECF 571
            ||:.:.:.:|.|..:..|.::|.:|.....|.:|..||.||.:.|    ||
  Rat   502 LSYLYFSAVGCLGCIAAGIIISFLTGRQRGKDVDPLLIRPVCNLF----CF 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	166/528 (31%)
Slc5a12	NP_001102058.1	SLC5sbd_SMCT2	3..527	CDD:212089	170/544 (31%)