DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33124 and SLC5A11

DIOPT Version :9

Sequence 1:	NP_001097056.3	Gene:	CG33124 / 318891	FlyBaseID:	FBgn0053124	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_609192.1	Gene:	SLC5A11 / 34117	FlyBaseID:	FBgn0031998	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	580	Identity:	388/580 - (66%)
Similarity:	476/580 - (82%)	Gaps:	4/580 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESS----PADTPEISIPNFGSKKMNEY 61
            |:.||||:|||.||||:.:||.:.|:|||.|||:|.::|.:    |..||:....:|||:||:||
  Fly     9 MENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEY 73

  Fly    62 LMGSGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSAL 126
            |:||.:|||||||||||||:||||.|||..||||.|||||..|.:||::||:||||:|:||||||
  Fly    74 LLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSAL 138

  Fly   127 QVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVI 191
            ||.||||||.||||.::|:|.|.||:::.:|:.||:|:|||:||||.||:|:|:|.|:|:||||.
  Fly   139 QVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVF 203

  Fly   192 YTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRN 256
            ||.:||:|||||||.|||::||.||:.||||||.|...|:..|:....||||||.|.|||||||:
  Fly   204 YTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRH 268

  Fly   257 TVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMY 321
            |||||:|||..||||..||:||||.||||||:||.||.|:|.|.:|...|.||..::||||:.||
  Fly   269 TVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMY 333

  Fly   322 KDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVR 386
            |||||||||.|.::|||:|||||||||||||:.||||||||||.||||||.|||||||||:||||
  Fly   334 KDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVR 398

  Fly   387 GCFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLV 451
            |||||||.|.||.|:||:|::::|.:....|.:||::|||||||.|:.|||..:|||:|||.:||
  Fly   399 GCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLV 463

  Fly   452 PWANTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVF 516
            ||||||||||||||..||.|||:||:|...|:|:|:..:|||||..|.||||.|||:||||||||
  Fly   464 PWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVF 528

  Fly   517 PLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNL 576
            ||:|||:|||||||..||:|||:|||||||||::|:||.||||||||||||||||..|||
  Fly   529 PLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGRNL 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	347/527 (66%)
SLC5A11	NP_609192.1	SLC5sbd_NIS-SMVT	17..556	CDD:271383	355/538 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473046
Domainoid	1	1.000	544	1.000	Domainoid score	I933
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	716	1.000	Inparanoid score	I1768
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900