Protein Alignment CG33124 and Gm5134

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_006513854.1
• Gene: Gm5134 / 333669
• MGIID: 3646667
• Length: 695
• Species: Mus musculus
• Alignment Length: 635
• Identity: 117/635 - (18%)
• Similarity: 226/635 - (35%)
• Gaps: 198/635 - (31%)

  Fly     8 TVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFP 72
            |.|..|.....:|.:.:||:                     ::.:.....:.::.:...:|..:.
Mouse    24 TTDTLVMTFYLLLVVCVGLW---------------------ALLSHSRGTVKDFFLAGQNLAWWL 67

  Fly    73 VAMSLIASFI-SG----VAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSY 132
            :.:|:.:|.| ||    :|.:|..|.|.....:::.|.:..::     .:|::|::|..:|.:..
Mouse    68 MGISIYSSNIGSGHYMALAGIGAASGIAVGALEWNSIFMLFLL-----GWIFVPIYSKAEVVTLP 127

  Fly   133 EYLGMRFHPL-IRNIVSIMFVIEVLLYTPFVVFV--PALALNQASGLNIHMIEVLIIVVCVIYTL 194
            |||..||..| |:...:.:|:| |.:::...:.:  .|:.|......:|:...:.::.:..:||:
Mouse   128 EYLKKRFGSLRIQLFFTFIFLI-VYIFSRISMEIGFGAMFLKMVWDTDIYQTMLTVLTIIGMYTI 191

  Fly   195 LGGLKAVVHTDIWQVVIMFASVVVVAILA-------------------------------TCYIT 228
            .|||..|.:.:..|..||.....::...|                               .||:.
Mouse   192 TGGLATVAYVESLQAGIMILGSALLMGYAFYEVGGYPKLVSKYMEAIPSKTQQGNWTAQPECYLP 256

  Fly   229 DLDDF--FESLVDGGRLIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVH----QTMVHRYMS-L 286
            ..|.|  |.|.|.|               :..|..:|.||   |:::..:    |..|.|::: .
Mouse   257 RQDAFHIFRSCVSG---------------DIPWPGLILGA---TTVSLFYGCADQVSVQRFLAGK 303

  Fly   287 PNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAGQIMNNDQLV------------ 339
            ..|.|.         |..:....|..|.:.:..|     |....:|:..||:.
Mouse   304 SRLHME---------GGCLLCGYLKLLPMFLMVM-----PGMISRILYPDQVACVVPSECQKFCG 354

  Fly   340 ----------PLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPG 394
                      |:.|:..:.|  |:.|..::.:..:.:|||:...||:|.:...:|...   ::|.
Mouse   355 RGTGCSALAYPVLVLGVMPH--GLQGFMLSTVCASLMSSLTSIFNSSSALFTLNIYTW---IRPT 414

  Fly   395 ETASAIIV--KATIVIMGALVFGEVLLLEKVSG--------ILSICMSLVAIATSSTFGIFTLAV 449
            .|...:::  :..::|:.|:....:.::|....        :|..|:      |.|...:|.|||
Mouse   415 ATEKELMIAGRFFVIILLAVTIVWIPIIEMAPNEILFEYMQVLKSCL------TPSMTAVFLLAV 473

  Fly   450 LVP--------WANTVGTAVG---------------------------------GIAGFLLTGWI 473
            ...        |...|||.:|                                 |...||:|..|
Mouse   474 FCKRVNEQGAFWGLIVGTTIGVFRLLAEFFYGPVTCGRDRQCPIFICGLHYLYFGFCLFLVTILI 538

  Fly   474 TFGSQIAAASGQLHH-HRLPVSVASCPGNVTARENVWVDEE---QVFPLF 519
            .....:|......|| |.|..|:.:     :.:..|.:|:|   :.||.|
Mouse   539 ILAISLATEPIPDHHLHGLCWSLRN-----SQQRRVALDKEMRWKAFPSF 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	116/634 (18%)
Gm5134	XP_006513854.1	SLC5-6-like_sbd	26..695	CDD:444915	116/633 (18%)