Protein Alignment CG33124 and Slc5a6

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_808538.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 610
• Identity: 190/610 - (31%)
• Similarity: 304/610 - (49%)
• Gaps: 69/610 - (11%)

  Fly     6 FGTVDYTVFLGVTILSIAIGLYF---GWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGH 67
            |..|||.||..:.:||:.||||.   ||                       |...:.|.||....
Mouse    23 FSVVDYVVFGLLLVLSLVIGLYHACRGW-----------------------GHHTVGELLMADRK 64

  Fly    68 LKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSY 132
            :...|||:||:|:|.|.|||||.|:||:.:||||..:..:..:..|..::|::|||..|.:.|:|
Mouse    65 MGCLPVALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAY 129

  Fly   133 EYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGG 197
            |||.:||:..:|...::.|:.::::|....::.|:||||..:|.::.:..:.:.:||.|||.|||
Mouse   130 EYLELRFNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGG 194

  Fly   198 LKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFG-NINPSPYVRNTVWSV 261
            ||||:.||::|.::||...:||.|:....:..|...:......| ||.| |::|.|:||:|.|::
Mouse   195 LKAVIWTDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHG-LISGINLDPDPFVRHTFWTL 258

  Fly   262 VIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTS-IAFFVLGSIIFYSVLSFLGLLIF---NMY- 321
            ..||.|...|:..|:|..|.||:|..:.:.|..| .|.|....:.. .:...:||::|   |||
Mouse   259 AFGGVFMMLSLYGVNQAQVQRYLSSHSERAAVLSCYAVFPCQQVAL-CMSCLIGLVMFAYYNMYS 322

  Fly   322 -----KDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVIL 381
                 |...|         ||||..||:..:..:.|:||||:|.:|...||::|...||.:.|.:
Mouse   323 MSPELKQAAP---------DQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTM 378

  Fly   382 QDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFT 446
            :|:::..|. |..||.:.::.:......|.:..|...:...:..:|...:|:..:......|:|.
Mouse   379 EDLIQPWFP-QLTETRAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFC 442

  Fly   447 LAVLVPWANTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVD 511
            |.:..|.||.:|..||.:.|..:..||..||.::..|..:....|..|.:..|.|||.     ..
Mouse   443 LGLFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAVAPPPLNGSSSFLPANVTV-----AA 502

  Fly   512 EEQVFP-----------LFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHR- 564
            ...|.|           .:.||:.|.:...:.||:|||.:|||:|.....:||:...|.||:.:
Mouse   503 VTTVMPSTLSKPTGLQHFYSLSYLWYSAHNSTTVIVVGLIVSLLTGGMRGRSLNPGTIYPVLPKL 567

  Fly   565 --FLPKECFKQRNLDKSEATDIYTI 587
              .||..| ::|...:|.:.||..|
Mouse   568 LALLPLSC-QKRLCWRSHSQDIPVI 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	167/548 (30%)
Slc5a6	NP_808538.1	SLC5-6-like_sbd	23..548	CDD:444915	176/564 (31%)