DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33124 and CG31262

DIOPT Version :9

Sequence 1:	NP_001097056.3	Gene:	CG33124 / 318891	FlyBaseID:	FBgn0053124	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	342/578 - (59%)
Similarity:	441/578 - (76%)	Gaps:	7/578 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGS 65
            ||.||||||||.|.:.:|:||...|:|||.:||..|..:|...|...   .||||:|::||||||
  Fly     1 MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRR---TNFGSEKIDEYLMGS 62

  Fly    66 GHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRS 130
            .::||.||:::|...    .:|:|.|||||:|||||.||::||::||:|.||:||||:||||:.|
  Fly    63 RNMKVIPVSITLYRV----TSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGS 123

  Fly   131 SYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLL 195
            :|||||:||:.:||...|.|:|..:|.|.||:|:||||:|:|.||||.|:|.::||:.||.||.:
  Fly   124 AYEYLGLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFM 188

  Fly   196 GGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVWS 260
            ||||||||||:|||.:||.|:|.||.||..|...|...|:....||||:..|.|||||||:||||
  Fly   189 GGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWS 253

  Fly   261 VVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCD 325
            |:|||..:|||:.|..|.||.||||||:||.:|.:...|.:|..||.::..|:|||:|:.|||||
  Fly   254 VLIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCD 318

  Fly   326 PLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFK 390
            |.|||.|:|:|||:|||||||||||||:|||||||||||||||||...|:.|:|.|:|||||.||
  Fly   319 PRSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFK 383

  Fly   391 MQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWAN 455
            |:|.|..|.|::|..|:..|.|.|..|.||:.:.||||:|.|:.:|...::||:|||.:|.||||
  Fly   384 MEPSERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWAN 448

  Fly   456 TVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFR 520
            |:||||||::..||.|||:||||||||||||....|||||..|.||||..|:.|||::|||||:|
  Fly   449 TIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYR 513

  Fly   521 LSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDK 578
            ||:||::|||.:|.||||:||||:|||.|||:|.::|||||||||||:|||:.|||::
  Fly   514 LSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGRNLNE 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	302/523 (58%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	299/519 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473048
Domainoid	1	1.000	544	1.000	Domainoid score	I933
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	716	1.000	Inparanoid score	I1768
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900