Protein Alignment CG33124 and Slc5a2

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_573517.1
• Gene: Slc5a2 / 246787
• MGIID: 2181411
• Length: 670
• Species: Mus musculus
• Alignment Length: 633
• Identity: 139/633 - (21%)
• Similarity: 254/633 - (40%)
• Gaps: 142/633 - (22%)

  Fly    10 DYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVA 74
            |..|.....:|.|.:||:                   .:...|.|:  :..|.:....:..:||.
Mouse    23 DILVIAAYFLLVIGVGLW-------------------SMFRTNRGT--VGGYFLAGRSMVWWPVG 66

  Fly    75 MSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEY 134
            .||.||.|.     |:|..|..|.:...|.:::.:.:.:::     .::::||:....|.:..:|
Mouse    67 ASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLL-----GWLFVPVYLTAGVITMPQY 126

  Fly   135 LGMRF--HPLIRNIVSIMFVIEVLLYTPFVV--FVPALALNQASGLNIHMIEVLIIVVCVIYTLL 195
            |..||  | .||..:|::.:. :.::|...|  |..|:.:.||.|.||:...:.::.:.:|||:.
Mouse   127 LRKRFGGH-RIRLYLSVLSLF-LYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVT 189

  Fly   196 GGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------SLVDGGRLIFGNINPSPY 253
            |||.|:::||..|..::.|...::...|...:......|:       ||........|||:.:.|
Mouse   190 GGLAALMYTDTVQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAMTSLTVSKDPSVGNISSTCY 254

  Fly   254 ---------VRNTV-----WSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFF 299
                     :|:.|     |..::.|     .:||.|    .|.:|.|.::..||...:...  .
Mouse   255 QPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCS----DQVIVQRCLAGKNLTHIKAGC--I 313

  Fly   300 VLGSI----IFYSVLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIY 351
            :.|.:    :|..|:.  |::...:|.|         |..:...::..::...|..||:.:.:
Mouse   314 LCGYLKLMPMFLMVMP--GMISRILYPDEVACVVPEVCKRVCGTEVGCSNIAYPRLVVKLMPN-- 374

  Fly   352 GIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQP--GETASAIIVKATIVIMGALVF 414
            |:.||.:|.:..|.:|||:...||:|.:...||..   :::|  |:....::.:..:|.:.|:..
Mouse   375 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYT---RLRPRAGDKELLLVGRLWVVFIVAVSV 436

  Fly   415 GEVLLLEKVSG--ILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLLTGWITFGS 477
            ..:.:::...|  :.....|:.:........:|.||:.||..|..| |..|:.|.||.|......
Mouse   437 AWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNEKG-AFWGLVGGLLMGLARLIP 500

  Fly   478 QIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLF-RLSFHWINPI-----GALTVVV 536
            :....||..      |..::||.                 || |:.:.:...|     |.||:.
Mouse   501 EFFFGSGSC------VRPSACPA-----------------LFCRVHYLYFAIILFICSGILTLG- 541

  Fly   537 VGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDI 584
                :||.|.|...|.|         ||.:    |..|: .|.|..|:
Mouse   542 ----ISLCTAPIPQKHL---------HRLV----FSLRH-SKEEREDL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	124/580 (21%)
Slc5a2	NP_573517.1	SLC5-6-like_sbd	22..670	CDD:444915	139/633 (22%)