DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33124 and Slc5a9

DIOPT Version :9

Sequence 1:	NP_001097056.3	Gene:	CG33124 / 318891	FlyBaseID:	FBgn0053124	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_663526.3	Gene:	Slc5a9 / 230612	MGIID:	2140201	Length:	685	Species:	Mus musculus

Alignment Length:	542	Identity:	120/542 - (22%)
Similarity:	224/542 - (41%)	Gaps:	109/542 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 YLMGSGHLKVFPVAMSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYL 120
            |.:....:..:|:..||::|.:.     |:|..|....:...|.:::...|.     ||:.:|::
Mouse    63 YFLAGRSMTWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATFLL-----LALGWIFV 122

  Fly   121 PVFSALQVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFV-----VFVPALALNQASGLNIHM 180
            ||:.|..|.:..:||..||..  :.|...|.|:.::||. |.     :|..||.:..|.|.|:::
Mouse   123 PVYIAAGVVTMPQYLKKRFGG--QRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMALGWNLYL 184

  Fly   181 IEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAIL----------------------- 222
            ..|:::||..:||:.|||.||::||..|.|||....:|:..|
Mouse   185 STVILLVVTAVYTIAGGLTAVIYTDALQTVIMVGGALVLMFLGFQEVGWYPGLQQLYRQAIPNTT 249

  Fly   223 ---ATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYM 284
               .||:: ...|.|..|.|.   :.|:| |.|   ..::.:.:...:.|    ...|.:|.|.:
Mouse   250 VPNTTCHL-PRPDAFHMLRDP---VNGDI-PWP---GLIFGLTVLATWCW----CTDQVIVQRSL 302

  Fly   285 SLPNLKMARTSIAFFVLGSII-----FYSVLSFLGLLIFNMYKD---------CDPLSAGQIMNN 335
            :..||..|:..   .|||..:     |:.|:.  |::...:|.|         |..:...::..:
Mouse   303 AAKNLSHAKGG---SVLGGYLKILPMFFIVMP--GMISRALYPDEVACVDPDICQRVCGARVGCS 362

  Fly   336 DQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAI 400
            :...|..|:..:.  .|:.||.||.|..|.:|||:...||:|.:...|:.:. |:.|..|....:
Mouse   363 NIAYPKLVMALMP--VGLRGLMIAVIMAALMSSLTSIFNSSSTLFAIDVWQR-FRRQASEQELMV 424

  Fly   401 IVKATIV--IMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGG 463
            :.:..:|  ::.::::..::.......:.....|:.:........:|.||:.....|..| |..|
Mouse   425 VGRLFVVFLVVISILWIPIIQSSNSGQLFDYIQSITSYLAPPITALFLLAIFCKRVNEPG-AFWG 488

  Fly   464 IAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWIN- 527
            :...|:.|.:....:.:            .|..:| |.:..|..|..|           ||::.
Mouse   489 LMFGLVVGILRMILEFS------------YSAPAC-GEMDRRPAVLKD-----------FHYLYF 529

  Fly   528 --PIGALTVVVVGSLVSLVTKP 547
              .:..||.::: .::|..|:|
Mouse   530 ALLLCGLTAIII-VVISFFTEP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	115/526 (22%)
Slc5a9	NP_663526.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SLC5-6-like_sbd	45..685	CDD:382020	120/542 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	577..616
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740