Protein Alignment CG33124 and Slc5a1

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_062784.3
• Gene: Slc5a1 / 20537
• MGIID: 107678
• Length: 665
• Species: Mus musculus
• Alignment Length: 642
• Identity: 132/642 - (20%)
• Similarity: 246/642 - (38%)
• Gaps: 155/642 - (24%)

  Fly    10 DYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVA 74
            |.:|.:...::.:|:||:         .|.|:...|            :..:.:....:..:|:.
Mouse    28 DISVIVIYFVVVMAVGLW---------AMFSTNRGT------------VGGFFLAGRSMVWWPIG 71

  Fly    75 MSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEY 134
            .||.||.|.     |:|..|..:.|...|.:::.:||.:|:     .:|::|::....|.:..||
Mouse    72 ASLFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVLVVVL-----GWIFVPIYIKAGVVTMPEY 131

  Fly   135 LGMRFHPLIRNIVSIMFVIEVLLYTPFV-----VFVPALALNQASGLNIHMIEVLIIVVCVIYTL 194
            |..||..  :.|...:.|:.:|||. |.     :|..|:.:|.|.||:|::...:::.:..:||:
Mouse   132 LRKRFGG--KRIQIYLSVLSLLLYI-FTKISADIFSGAIFINLALGLDIYLAIFILLAITALYTI 193

  Fly   195 LGGLKAVVHTDIWQVVIMFASVVVVAILA-------------------------------TCYIT 228
            .|||.||::||..|..||.....::...|                               .||..
Mouse   194 TGGLAAVIYTDTLQTAIMLVGSFILTGFAFNEVGGYEAFMDKYMKAIPTKVSNGNFTAKEECYTP 258

  Fly   229 DLDDF--FESLVDGGR----LIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLP 287
            ..|.|  |...:.|..    ||||              :.|...:||    ...|.:|.|.:|..
Mouse   259 RADSFHIFRDPITGDMPWPGLIFG--------------LAILALWYW----CTDQVIVQRCLSAK 305

  Fly   288 NL---KMARTSIAFFVLGSIIFYSVLSFLGLLIFN------MYKDCDPLSAGQIMNNDQLVPLFV 343
            |:   |...|...:..|..:....:...:..:::.      :.::|.......:...:...|..|
Mouse   306 NMSHVKAGCTLCGYLKLLPMFLMVMPGMISRILYTEKIACVLPEECQKYCGTPVGCTNIAYPTLV 370

  Fly   344 VQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKA---T 405
            |:.:.:  |:.||.::.:..:.:|||:...||.|.:...||..   |::...:...:::..   .
Mouse   371 VELMPN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYT---KIRKKASEKELMIAGRLFI 430

  Fly   406 IVIMGALVFGEVLLLEKVSG-ILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLL 469
            :|::|..:....::....|| :.....|:.:........:|.||:.....|..|...|.|.|||:
Mouse   431 LVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEQGAFWGLILGFLI 495

  Fly   470 TGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTV 534
             |.....::.|..:|..      :..::||..:.....::.    ...||.:|        .:|:
Mouse   496 -GISRMITEFAYGTGSC------MEPSNCPKIICGVHYLYF----AIILFVIS--------VITI 541

  Fly   535 VVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRN-------LDKSEATDI 584
            ::    :|.:|||.           |.:|  |.:.|:..||       ||..|..||
Mouse   542 LI----ISFLTKPI-----------PDVH--LYRLCWSLRNSKEERIDLDAGEEEDI 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	116/582 (20%)
Slc5a1	NP_062784.3	SLC5-6-like_sbd	27..665	CDD:294310	132/642 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836548
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750