Protein Alignment CG33124 and SLC5A9

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_011539226.1
• Gene: SLC5A9 / 200010
• HGNCID: 22146
• Length: 719
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 128/587 - (21%)
• Similarity: 225/587 - (38%)
• Gaps: 161/587 - (27%)

  Fly    61 YLMGSGHLKVFPVAMSLIAS------FI--------SGVAILG----------------NP---- 91
            |.:....:..:|:..||::|      ||        .|:|:.|                :|
Human    67 YFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHG 131

  Fly    92 -----SEIYYYG------TQYSLIV---LAIVIQG----------------LAVSYIYLPVFSAL 126
                 |::.|:.      .|:.|.|   .::.||.                ||:.::::||:.|.
Human   132 RTGVRSQVSYFSVRGPPTAQHCLWVGSRPSVYIQDLDTFFFSPLSQATWLLLALGWVFVPVYIAA 196

  Fly   127 QVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFV-----VFVPALALNQASGLNIHMIEVLII 186
            .|.:..:||..||..  :.|...|.|:.::||. |.     :|..||.:..|.|.|:::...:::
Human   197 GVVTMPQYLKKRFGG--QRIQVYMSVLSLILYI-FTKISTDIFSGALFIQMALGWNLYLSTGILL 258

  Fly   187 VVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILA---TCYITDLDDFFESLVDGGRLIFGNI 248
            ||..:||:.|||.||::||..|.|||....:|:..|.   ..:...|:..:...:
Human   259 VVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAI---------- 313

  Fly   249 NPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSII-----FYS 308
             |:..|.||...:....||:    ......:|.|.:|..:|..|:..   .|||..:     |:.
Human   314 -PNVTVPNTTCHLPRPDAFH----ILRDPVIVQRSLSAKSLSHAKGG---SVLGGYLKILPMFFI 370

  Fly   309 VLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGA 364
            |:.  |::...::.|         |..:...::..::...|..|:..:.  .|:.||.||.|..|
Human   371 VMP--GMISRALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAA 431

  Fly   365 GLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLE-----KVS 424
            .:|||:...||:|.:...|:.:. |:.:..|....::.:..:|.:..:....:.:::     ::.
Human   432 LMSSLTSIFNSSSTLFTIDVWQR-FRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLF 495

  Fly   425 GILSICMSLVAIATSSTF--GIFTLAVLVP---WANTVGTAVGGIAGFLLTGWITFGSQIAAASG 484
            ..:....|.:|...::.|  .||...|..|   |....|..||     ||...:.| |..|.|.|
Human   496 DYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFGLGVG-----LLRMILEF-SYPAPACG 554

  Fly   485 QLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHW----INPIGALTVVVVGSLVSLVT 545
            :                        ||..   |.....||:    |...|...:|:|  :|||.|
Human   555 E------------------------VDRR---PAVLKDFHYLYFAILLCGLTAIVIV--IVSLCT 590

  Fly   546 KP 547
            .|
Human   591 TP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	121/571 (21%)
SLC5A9	XP_011539226.1	SLC5-6-like_sbd	37..719	CDD:294310	128/587 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750