Protein Alignment CG33124 and Slc5a6

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_570102.1
• Gene: Slc5a6 / 170551
• RGDID: 69648
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 187/607 - (30%)
• Similarity: 303/607 - (49%)
• Gaps: 49/607 - (8%)

  Fly     2 DTYR----FGTVDYTVFLGVTILSIAIGLYF---GWIKKTKKEMESSPADTPEISIPNFGSKKMN 59
            ||.|    |..|||.||..:.:||:.||||.   ||                       |...:.
  Rat    15 DTNRVISTFSVVDYVVFGLLLVLSLVIGLYHACRGW-----------------------GRHTVG 56

  Fly    60 EYLMGSGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFS 124
            |.||....:...|||:||:|:|.|.|||||.|:|||.:||||..:..:..:..|..::|::|||.
  Rat    57 ELLMADRKMGCLPVALSLLATFQSAVAILGGPAEIYRFGTQYWFLGCSYFLGLLIPAHIFIPVFY 121

  Fly   125 ALQVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVC 189
            .|.:.|:||||.:||:..:|...::.|:.::::|....::.|:||||..:|.::.:..:.:.:||
  Rat   122 RLHLTSAYEYLELRFNKAVRICGTVTFIFQMVVYMGVALYAPSLALNAVTGFDLWLSVLALGIVC 186

  Fly   190 VIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFG-NINPSPY 253
            .|||.|||||||:.||::|.:|||...:||.|:....:..|...:......| ||.| .::|.|:
  Rat   187 NIYTALGGLKAVIWTDVFQTLIMFLGQLVVIIVGAAKVGGLGHVWAVASQHG-LISGIELDPDPF 250

  Fly   254 VRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTS-IAFFVLGSIIFYSVLSFLGLLI 317
            ||:|.|::..||.|...|:..|:|..|.||:|..:.|.|..| .|.|....:.. .:...:||::
  Rat   251 VRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSHSEKAAVLSCYAVFPCQQVAL-CMSCLIGLVM 314

  Fly   318 FNMYKDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQ 382
            |..||........:....||||..||:..:..:.|:||||:|.:|...||::|...||.:.|.::
  Rat   315 FAYYKKYSMSPQQEQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTME 379

  Fly   383 DIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTL 447
            |:::..|. |..||.:.::.::.....|.:..|...:...:..:|...:|:..:......|:|.|
  Rat   380 DLIQPWFP-QLTETRAIMLSRSLAFAYGLVCLGMAYVSSHLGSVLQAALSIFGMVGGPLLGLFCL 443

  Fly   448 AVLVPWANTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVT-ARENVWVD 511
            .:..|.||.:|..||.:.|..:..||..||.::..|.......|..|.:..|.|:| |.....:.
  Rat   444 GMFFPCANPLGAIVGLLTGLTMAFWIGIGSIVSRMSSAAASPPLNGSSSFLPSNLTVATVTTLMP 508

  Fly   512 EEQVFP-----LFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFL----- 566
            .....|     .:.||:.|.:...:.||:.||.:|||:|.....:||:...|.||:.:.|
  Rat   509 STLSKPTGLQQFYSLSYLWYSAHNSTTVIAVGLIVSLLTGGMRGRSLNPGTIYPVLPKLLALLPL 573

  Fly   567 ---PKECFKQRNLDKSEATDIY 585
               .:.|::..|.|....|:::
  Rat   574 SCQKRLCWRSHNQDIPVVTNLF 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	165/534 (31%)
Slc5a6	NP_570102.1	SLC5-6-like_sbd	23..548	CDD:444915	173/550 (31%)