Protein Alignment CG33124 and SLC5A10

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 718
• Identity: 149/718 - (20%)
• Similarity: 258/718 - (35%)
• Gaps: 244/718 - (33%)

  Fly     2 DTYRFGT----VDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYL 62
            |.:..||    .|..|......|::|:|::                     |........:|.|.
Human     8 DLHTPGTQLSVADIIVITVYFALNVAVGIW---------------------SSCRASRNTVNGYF 51

  Fly    63 MGSGHLKVFPVAMSLIAS------FI--------SGVAILGNPSEIYYYGTQYSLIVLAIVIQGL 113
            :....:..:|:..||.||      ||        .|:|:.|     :.:...|.|         |
Human    52 LAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAG-----FEWNATYVL---------L 102

  Fly   114 AVSYIYLPVFSALQVRSSYEYLGMRF-HPLIRNIVSIM-FVIEVLLYTPFVVFVPALALNQASGL 176
            |::::::|::.:.::.:..||:..|: ...||..:|:: .::.|.......::..||.::...|.
Human   103 ALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGW 167

  Fly   177 NIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGG 241
            |.::..:|.:.:..:||:.|||.||::||..|.:||....|::.|.|          |:.:...|
Human   168 NFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKA----------FDQIGGYG 222

  Fly   242 RL--IFGNINPSPYVRNTV---------------------WS-----VVIGGAFYWTSITAVHQT 278
            :|  .:....||..:.||.                     |:     :.|...:||    ...|.
Human   223 QLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYW----CTDQV 283

  Fly   279 MVHRYMSLPNLKMARTSIAFFVLGSII-FYSVLSFLGLLIF------------NMYKDCDPLSAG 330
            :|.|.:|..:|..|:.       |||: .|..:..:||:|.            ::|::...:|..
Human   284 IVQRSLSARDLNHAKA-------GSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVS 341

  Fly   331 QIMNNDQLVPLFVVQSVG------HI-----------YGIPGLFIAGIFGAGLSSLSVFLNSTSL 378
            :..:...:||...:::.|      :|           .|:.||.||.:..|.:|||:...||:|.
Human   342 RTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSST 406

  Fly   379 VILQDIVRGCFKMQP--GETASAII----VKAT-------------------------------- 405
            :...||.|   :::|  ||....::    :.:|
Human   407 LFTMDIWR---RLRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWL 468

  Fly   406 --IVIMGALVFGEVLLLEKVSGILSICMSLVAIATSS----TFGIFTLAVLVPWANTVGTAVGGI 464
              :.::|..|....:|.:..||.|.|.|..|   |||    ...:|.|.|....||..|...|.|
Human   469 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSV---TSSLAPPVTAVFVLGVFWRRANEQGAFWGLI 530

  Fly   465 AGFLLTGWITFGSQI-------------AAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVF 516
            || |:.|......:.             .|..|.:|:....|:
Human   531 AG-LVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVA---------------------- 572

  Fly   517 PLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLD--------------SDLISPVIHRFLP 567
             ||.||       ||  |||.|||::...:...|::|.              .|..:|..|.|..
Human   573 -LFALS-------GA--VVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWA 627

  Fly   568 KEC 570
            :.|
Human   628 RVC 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	133/654 (20%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:444915	146/709 (21%)