Protein Alignment CG33124 and SLC5A11

DIOPT Version :9

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_001339171.1
• Gene: SLC5A11 / 115584
• HGNCID: 23091
• Length: 675
• Species: Homo sapiens
• Alignment Length: 625
• Identity: 137/625 - (21%)
• Similarity: 243/625 - (38%)
• Gaps: 156/625 - (24%)

  Fly    10 DYTVFLGVTILSIAIGLYFGW-IKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPV 73
            |..|.:...:..:|:||   | ..|||:       ||            :..|.:..|.:..:||
Human    28 DIAVLVLYFLFVLAVGL---WSTVKTKR-------DT------------VKGYFLAGGDMVWWPV 70

  Fly    74 AMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQG----LAVSYIYLPVFSALQVRSSYEY 134
            ..||.||.:.....:|....    |....:.|.|..:.|    |.:::|:||::.|.||.:..||
Human    71 GASLFASNVGSGHFIGLAGS----GAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEY 131

  Fly   135 LGMRFHPLIRNIVSIMFVIEVLLYTPFVV--FVPALALNQASGLNIHMIEVLIIVVCVIYTLLGG 197
            |..||..:...|:..:..:.:.::|...|  :..|:.:.|:..|::::..|.::.:..:||:.||
Human   132 LRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGG 196

  Fly   198 LKAVVHTDIWQVVIM-----------FASVVVVAILATCYITDL--------------DDFFESL 237
            |.||::||..|.:||           ||:|..:..|...|...|              :|.|...
Human   197 LAAVIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIF 261

  Fly   238 VDGGRLIFGNINPSPYVRNTVWSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTSIA 297
            .|            |...:..|..|:.|     .:||    ...|.:|.|.::..||..|:....
Human   262 RD------------PLTSDLPWPGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGAL 310

  Fly   298 FFVLGSIIFYSVLSFLGLLIFNMYKD----CDPLSAGQIMNN-----DQLVPLFVVQSVGHIYGI 353
            ......::...::.|.|::...::.|    .||....:|.:|     |...|..|::.:.  .|:
Human   311 MAAYLKVLPLFIMVFPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLP--TGL 373

  Fly   354 PGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVL 418
            .||.:|.:..|.:|||:...||.|.:...|:..   .::|..:...:::...:.:: .||...:|
Human   374 RGLMMAVMVAALMSSLTSIFNSASTIFTMDLWN---HLRPRASEKELMIVGRVFVL-LLVLVSIL 434

  Fly   419 LLEKV----SGILSICMSLVA------IATSSTFGIFTLAVLVPW--ANTVGTAVGGIAGFLLTG 471
            .:..|    .|.|.|.:..::      :|.....|.|       |  .|..|...|.|:|.|| |
Human   435 WIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCF-------WKRTNEKGAFWGLISGLLL-G 491

  Fly   472 WITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWV----DEEQVFPLFRLSFHWI---NPI 529
            .:                ||.:            :.::|    |:....|:...|.|::   ..:
Human   492 LV----------------RLVL------------DFIYVQPRCDQPDERPVLVKSIHYLYFSMIL 528

  Fly   530 GALTVVVVGSLVSLVTKPTDIKSLDSDLI-----SPVIHR 564
            ..:|::.| |.||..|:|.. |.:.|.|.     .||:.:
Human   529 STVTLITV-STVSWFTEPPS-KEMVSHLTWFTRHDPVVQK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	125/587 (21%)
SLC5A11	NP_001339171.1	SLC5sbd_SGLT6	28..675	CDD:271381	137/625 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146470
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850