Protein Alignment CG33124 and slc5a11

DIOPT Version :10

• Sequence 1: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_004918107.1
• Gene: slc5a11 / 100488766
• XenbaseID: XB-GENE-1010719
• Length: 674
• Species: Xenopus tropicalis
• Alignment Length: 627
• Identity: 138/627 - (22%)
• Similarity: 252/627 - (40%)
• Gaps: 157/627 - (25%)

  Fly     8 TVDYTVFLGVTILSIAIGLYFGW-IKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVF 71
            |||..|.:...:..:.:||   | |.:||:                 |:.|  .|.:....:..:
 Frog    25 TVDIVVLVLYFVFVLGVGL---WSICRTKR-----------------GTVK--GYFLAGKDMAWW 67

  Fly    72 PVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQG----LAVSYIYLPVFSALQVRSSY 132
            ||..||.||.:.....:|....    |....:.|.|....|    ||:::::||::.:..|.:..
 Frog    68 PVGASLFASNVGSGHFIGLAGS----GAASGIAVTAYEWNGLFCVLALAWLFLPIYISAGVTTMP 128

  Fly   133 EYLGMRF-HPLIRNIVSIMFVIEVLLYTPFVV--FVPALALNQASGLNIHMIEVLIIVVCVIYTL 194
            |||..|| ...|:..::|:::. :.::|...|  :..||.:.||...::::..:.::|:..|||:
 Frog   129 EYLQRRFGGKRIQIFLAILYLF-IYIFTKISVDMYAGALFIQQALQWDLYVAVIGLLVITAIYTV 192

  Fly   195 LGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDL----DDFFESL--VDGGRLIFG------- 246
            .|||.||::||..|.|||....:::...:...|...    :.:|:::  ...|....|
 Frog   193 AGGLAAVIYTDTLQTVIMIIGALILMAYSFIEIGGFEALQEKYFQAIPNTHSGNSTCGIPREDAF 257

  Fly   247 NINPSPYVRNTVWSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSI-- 304
            :|...|...:..|..|:.|     .:||    ...|.:|.|.:|..||..|:.       ||:
 Frog   258 HIFRDPVTSDLPWPGVLVGMTIPSLWYW----CTDQVIVQRSLSAKNLSHAKG-------GSLLA 311

  Fly   305 -------IFYSVL-SFLGLLIFNMYKDC-DPLSAGQIMNN-----DQLVPLFVVQSVGHIYGIPG 355
                   :|..|| ..:..::|.....| ||....:|..|     |...|..|::.:.  .|:.|
 Frog   312 ASLKVLPLFMMVLPGMISRVLFTDQVACADPELCKEICGNPSGCSDIAYPKMVIELLP--TGLRG 374

  Fly   356 LFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVF------ 414
            |.::.:..|.:|||:...||.|.:...|:.|   .::|..|...:::...:.::..:|.
 Frog   375 LMMSVMIAALMSSLTSIFNSASTIFTMDLWR---HIRPRSTEWELMIVGRVFVLALVVVSILWIP 436

  Fly   415 -------GEVLL-LEKVSGILSICMSLVAIA-----TSSTFGIFTLAVLVPWANTVGTAVGGIAG 466
                   |::.: ::.:|..|...:::|.||     .::..|.|       |..|:|.|||.|.
 Frog   437 LVQASQGGQLFIYIQSISSYLQPPVAVVFIAGCFWKRTNEKGAF-------WGMTIGLAVGLIR- 493

  Fly   467 FLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWI---NP 528
             ::..:|....|                   |            |:....|......|::   ..
 Frog   494 -MVLDFIYVAPQ-------------------C------------DQPDTRPGVVKYVHYLYLSMI 526

  Fly   529 IGALTVVVVGSLVSLVTKP---------TDIKSLDSDLISPV 561
            :|.||::||.: ||:.|:|         |.....|::::.||
 Frog   527 LGLLTLIVVVA-VSIWTEPPSKQMISRLTWFSRFDTEVVGPV 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	125/587 (21%)
slc5a11	XP_004918107.1	SLC5sbd_SGLT6	27..674	CDD:271381	136/625 (22%)