DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33124 and slc5a7a

DIOPT Version :9

Sequence 1:	NP_001097056.3	Gene:	CG33124 / 318891	FlyBaseID:	FBgn0053124	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	XP_021332411.1	Gene:	slc5a7a / 100005589	ZFINID:	ZDB-GENE-090313-273	Length:	592	Species:	Danio rerio

Alignment Length:	574	Identity:	123/574 - (21%)
Similarity:	211/574 - (36%)	Gaps:	155/574 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGS 65
            |:.:..|.|...:|.   :|.:.:|::..|..|....||              |:.:....::|.
Zfish     1 MNIHVEGLVAIVIFY---LLILLVGIWAAWKNKNSGVME--------------GTDRSETIMVGG 48

  Fly    66 GHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRS 130
            ..:.:|..|.::.|:::.|.         |..||               ..|:|||.|.....::
Zfish    49 RDIGLFVGAFTMTATWVGGG---------YINGT---------------AEYVYLPGFGLAWAQA 89

  Fly   131 SYEY-----LGMRF--HPL-IRNIVSIMFVIEVLLYTPF----------VVFVPAL--------A 169
            .:.|     ||..|  .|: .|..|:::        .||          ::|:|||        |
Zfish    90 PFGYALSLVLGGLFFAKPMRSRGYVTML--------DPFQQLYGKRMGGLLFIPALMGEMFWSAA 146

  Fly   170 LNQASG--------LNIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFAS--VVVVAILAT 224
            :..|.|        ::|:|..|:..::.:.|||:|||.:|.:||:.|:..:|..  |.|...|:.
Zfish   147 ILSALGATLSVIIDIDINMSVVISALIAIFYTLVGGLYSVAYTDVVQLFCIFLGLWVSVPFALSN 211

  Fly   225 CYITDLD-DFFESLVDGGRLIFGNINPSPYVRNTVWS-----VVIGGAFYWTSITAVHQTMVHRY 283
            ..::|:. ...:.|........|.|..|.   ..:|:     :::|| ..|       |....|.
Zfish   212 PAVSDIGVTAVKQLHANQTAWLGKIESSD---KWMWADNFCLLMLGG-IPW-------QVYFQRV 265

  Fly   284 MSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAGQI--MNNDQ---LVPLFV 343
            :|..:...|:........|.||.......:|.:  ....|.:..|.|.|  |..||   ::|: |
Zfish   266 LSASSATYAQVLSFLAAFGCIIMAIPSVLIGAI--GASTDWNQTSYGPIPPMQKDQSDMILPI-V 327

  Fly   344 VQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVI 408
            :|.:...| |....:..:..|.:||....:.|.|.:..::|.:..|:....:.....:::.||.:
Zfish   328 LQHLCPAY-ISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLAFRQSASDREIVWVMRITIFV 391

  Fly   409 MGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIF--TLAVL-VPWANTVGTAVGGIAGFLL- 469
            .|||.....||...|.|:..:...||.:.      ||  .|:|| :...||.|:..|...|.:|
Zfish   392 FGALATAMALLTGTVYGLWYLSSDLVYVI------IFPQLLSVLFIRGTNTYGSVAGYFFGLILR 450

  Fly   470 ----------------TGWITFGSQIAAASGQLHH----------HRLPVSVAS 497
                            .||        ....::||          .|.|...||
Zfish   451 IGGGEPYLKLPPFIYYPGW--------TIEEKVHHLTHEVEYLVMQRFPFKTAS 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	121/566 (21%)
slc5a7a	XP_021332411.1	SLC5sbd_CHT	8..508	CDD:271368	121/567 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840