DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-2 and Tmed11

DIOPT Version :9

Sequence 1:	NP_001189205.1	Gene:	p24-2 / 318890	FlyBaseID:	FBgn0053105	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	XP_001071744.1	Gene:	Tmed11 / 689712	RGDID:	1588776	Length:	214	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	91/204 - (44%)
Similarity:	139/204 - (68%)	Gaps:	7/204 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LILCVLHS-ACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEVR 73
            ::||...| :...|||..:.|.||.||::|.:|.:...:|::.:|...:.|:.|:||:||.|.|.
  Rat     6 ILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKIQQWDIGRHDFLESAPGLGMFVTVT 70

  Fly    74 DSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAW--FSGAQLRVHLDIQVGEHAIDYAHV 136
            ::|: ::||::|.:||...||||:.|||:||:.||||.:  |.|::||:||||:||||.:|...|
  Rat    71 NNDE-VLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAVIV 134

  Fly   137 AQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFW 201
            ..|:|:.|:...:|.|::|:|||.|||:|||.|||.||.|||.||..||||:.||.::.:.:|.:
  Rat   135 QAKDKVNEVAFTLRHLIEQIEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIF 199

  Fly   202 ---HLFNLF 207
               ||.:.|
  Rat   200 QMKHLKDFF 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-2	NP_001189205.1	EMP24_GP25L	20..206	CDD:279450	87/190 (46%)
Tmed11	XP_001071744.1	EMP24_GP25L	17..208	CDD:395878	87/191 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1690
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53581
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X178
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.780