DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment p24-2 and tmed9

DIOPT Version :9

Sequence 1:	NP_001189205.1	Gene:	p24-2 / 318890	FlyBaseID:	FBgn0053105	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	XP_005173235.1	Gene:	tmed9 / 613145	ZFINID:	ZDB-GENE-050417-434	Length:	223	Species:	Danio rerio

Alignment Length:	214	Identity:	129/214 - (60%)
Similarity:	167/214 - (78%)	Gaps:	7/214 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRDQFISLALILCVLHSA--CGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSS 63
            :|.||....|:|..::::  ..|||||.:||:||||||:||||.:|.||:.:|||.:...::|::
Zfish     4 IRMQFTLYFLVLLNIYNSLVSALYFHIGETEKKCFIEEIPDETMIIGNYRTQLYDKQKEEYLPAT 68

  Fly    64 PGIGMHVEVRDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNST--AWFSGAQLRVHLDIQV 126
            .|:||.|||:|.|:|::|||.|.|:||..|||||||||.||:.|||:  |.|:|..|||||||||
Zfish    69 QGLGMFVEVKDPDEKVILSRQYGSEGRFIFTSHTPGEHQICLHSNSSKFALFAGGMLRVHLDIQV 133

  Fly   127 GEHAIDYAHVAQKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQ 191
            |||..:||.:|.|:||||||||:|||::||:||.||||||||||||||.||||||.||||||:.|
Zfish   134 GEHTNNYAEIAAKDKLTELQLRVRQLMEQVDQIQKEQNYQRYREERFRQTSESTNQRVLWWSIVQ 198

  Fly   192 TVVLVCMGFW---HLFNLF 207
            |::||.:|||   ||.:.|
Zfish   199 TLILVAIGFWQMRHLKSFF 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-2	NP_001189205.1	EMP24_GP25L	20..206	CDD:279450	123/190 (65%)
tmed9	XP_005173235.1	EMP24_GP25L	25..218	CDD:279450	124/193 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	291	1.000	Domainoid score	I1497
eggNOG	1	0.900	-	-		E1_KOG1690
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2657
OMA	1	1.010	-	-		QHG53581
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001070
OrthoInspector	1	1.000	-	-		mtm6359
orthoMCL	1	0.900	-	-		OOG6_102210
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X178
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.770