DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p24-2 and tmed-4

DIOPT Version :9

Sequence 1:	NP_001189205.1	Gene:	p24-2 / 318890	FlyBaseID:	FBgn0053105	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_507861.1	Gene:	tmed-4 / 180307	WormBaseID:	WBGene00013360	Length:	211	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	135/199 - (67%)
Similarity:	166/199 - (83%)	Gaps:	1/199 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LALILCVLHSACGLYFHISQTERKCFIEEVPDETTVIVNYKVELYDPRSNGFMPSSPGIGMHVEV 72
            |..:|.:...|..|||||::||:||||||:||||.|..||||:||||.:.|: ...|.|||||||
Worm     4 LIALLSLATYADSLYFHIAETEKKCFIEEIPDETMVTGNYKVQLYDPNTKGY-GDYPNIGMHVEV 67

  Fly    73 RDSDDKIVLSRVYSSQGRISFTSHTPGEHVICMFSNSTAWFSGAQLRVHLDIQVGEHAIDYAHVA 137
            :|.:||::||::|:::||.:|||:||||||||::|||||||:|||||||||||.|:||.|||.:|
Worm    68 KDPEDKVILSKLYTAEGRFTFTSNTPGEHVICIYSNSTAWFNGAQLRVHLDIQAGDHAQDYAQIA 132

  Fly   138 QKEKLTELQLRIRQLLDQVEQITKEQNYQRYREERFRHTSESTNSRVLWWSLAQTVVLVCMGFWH 202
            ||:||.|||||||||||||:|||||||||||||||||.|||||||||.:||:||.|||...|.|.
Worm   133 QKDKLNELQLRIRQLLDQVDQITKEQNYQRYREERFRQTSESTNSRVFYWSIAQVVVLAITGAWQ 197

  Fly   203 LFNL 206
            :.:|
Worm   198 MRHL 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p24-2	NP_001189205.1	EMP24_GP25L	20..206	CDD:279450	131/185 (71%)
tmed-4	NP_507861.1	EMP24_GP25L	16..206	CDD:366467	132/187 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	301	1.000	Domainoid score	I766
eggNOG	1	0.900	-	-		E1_KOG1690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5308
Inparanoid	1	1.050	311	1.000	Inparanoid score	I1549
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53581
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001070
OrthoInspector	1	1.000	-	-		otm14332
orthoMCL	1	0.900	-	-		OOG6_102210
Panther	1	1.100	-	-	O	PTHR22811
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X178
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.830