DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tengl1 and Exog

DIOPT Version :9

Sequence 1:	NP_722780.1	Gene:	Tengl1 / 318883	FlyBaseID:	FBgn0051682	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_006244150.2	Gene:	Exog / 301062	RGDID:	1304628	Length:	443	Species:	Rattus norvegicus

Alignment Length:	230	Identity:	60/230 - (26%)
Similarity:	97/230 - (42%)	Gaps:	43/230 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 KYGFPSTNDITINETFDFVTSFDRRNSAILWMCERVDLSNRVVYGDST----------------- 129
            ::|||.|...|...| :...|:|:......|:.|.:  |...:.||:.
  Rat   139 QFGFPLTGTETRRYT-NHALSYDQAKRVPRWVLEHI--SKDKIIGDADRKHCKFKPDPTVPSAFS 200

  Fly   130 --------------SVAPAG--AFGQSEAARVFFLSNIRP--FLNRGFNLTVWDRLLQYVHEMSQ 176
                          .:||||  .|.....|..|:||||.|  |.|   |...|:|:..|..|:::
  Rat   201 ALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFEN---NSGYWNRIEMYCRELTE 262

  Fly   177 RHGTVYAYTGSIYLPRELKSNSWFLEFQSEERTMVAVPTHFFKILVIDKKFAGDTIPYA-EAYVM 240
            |...|:..:|.:.||......:..:.:|......||||:|.:|: ::.::....|.|.| .|:|:
  Rat   263 RFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKV-ILARRSPESTEPLALGAFVV 326

  Fly   241 PNSPLNNNVELKTLLSDVREIENATGLRFFEGLDR 275
            ||..:....:|......:.::|..:||.||..|||
  Rat   327 PNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPHLDR 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tengl1	NP_722780.1	Endonuclease_NS	98..275	CDD:214889	52/212 (25%)
Exog	XP_006244150.2	NUC	152..361	CDD:214683	53/215 (25%)
Exog	XP_006244150.2	Exog_C	377..425	CDD:407864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1864
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D570297at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820