Protein Alignment CG31681 and PRSS2

DIOPT Version :10

• Sequence 1: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 88/270 - (32%)
• Similarity: 137/270 - (50%)
• Gaps: 30/270 - (11%)

  Fly     7 LSILVSIAGLACAARIP-GPEERIVGGSYIPIEYVPWQVSVQNNSLHCCGGVIYSDRAILTAAHC 70
            :::|:.:..:|.|...| ..:::||||.......||:|||: |:..|.|||.:.|::.:::|.||
Human     1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHC 64

  Fly    71 LSNVTVTDLSVRAGSSYWS-------------KGG-QVLKVLKTIAHPKYVPKLYNPYDIAVLIL 121
            ..:...:.||.| |..|..             :|. |.:...|.|.||||..:..: .||.::.|
Human    65 YKSAINSKLSGR-GCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLD-NDILLIKL 127

  Fly   122 EAPLRLGGTVKKIPLAEQTPVAGTIVLTSGWGYTRENSSFLWPILQGVHVAILNRTDCLKAYKHV 186
            .:|..:...|..|.|....|.|||..|.||||.|..:.:.....||.:...:|::.:|..:|..
Human   128 SSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG- 191

  Fly   187 NITIDMICA---DGQRWDTCQGDSGGPLIETTKGGHRQLIGMVSWGDGCG--TNPGVYEDIAFFH 246
            .||.:|.|.   :|.: |:||||||||::     .:.:|.|:||||.||.  ..||||..:..:.
Human   192 KITNNMFCVGFLEGGK-DSCQGDSGGPVV-----SNGELQGIVSWGYGCAQKNRPGVYTKVYNYV 250

  Fly   247 NWIKYTVKKN 256
            :|||.|:..|
Human   251 DWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	79/239 (33%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	82/241 (34%)