back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31681 and TMPRSS7

DIOPT Version :10

Sequence 1:	NP_722789.1	Gene:	CG31681 / 318882	FlyBaseID:	FBgn0051681	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	261	Identity:	83/261 - (31%)
Similarity:	122/261 - (46%)	Gaps:	39/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GLACAARIPGPEERIVGGSYIPIEYVPWQVSVQNNSLHCCGGVIYSDRAILTAAHCLSNVTVTD- 78
            |..| :|......||:||:.......|||||:.......||..:.|...:|:||||.....::|
Human   593 GCTC-SRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDP 656

  Fly    79 --------LSVRAGSSYWSKGGQVLKVLKTIAHPKYVPKLYNPYDIAVLILEAPLRLGGTVKK-- 133
                    :.|:..:.:      |..|.:.:.|..|..:.:: ||||  :|:..:....|:|:
Human   657 TPWTAHLGMYVQGNAKF------VSPVRRIVVHEYYNSQTFD-YDIA--LLQLSIAWPETLKQLI 712

  Fly   134 ----IPLAEQTPVAGTIVLTSGWG--YTRENSSFLWPILQGVHVAILNRTDCLKAYKHVNITIDM 192
                ||...|...:|.....:|||  :..:|...|  :||...|.::::|.|:..|.  .||..|
Human   713 QPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSL--VLQQAEVELIDQTLCVSTYG--IITSRM 773

  Fly   193 ICA---DGQRWDTCQGDSGGPLIETTKG-GHRQLIGMVSWGDGCG--TNPGVYEDIAFFHNWI-K 250
            :||   .|:| |.|:|||||||....|. |...|.|:||||.|.|  ..||||..::.|..|| |
Human   774 LCAGIMSGKR-DACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHK 837

  Fly   251 Y 251
            |
Human   838 Y 838

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.