DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31681 and Klk12

DIOPT Version :9

Sequence 1:	NP_722789.1	Gene:	CG31681 / 318882	FlyBaseID:	FBgn0051681	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	XP_008757573.1	Gene:	Klk12 / 308564	RGDID:	1308975	Length:	247	Species:	Rattus norvegicus

Alignment Length:	271	Identity:	88/271 - (32%)
Similarity:	129/271 - (47%)	Gaps:	41/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRLLLSILVSIAGLACAARIPGPEERIVGGSYIPIEYV----PWQVSVQNNSLHCCGGVIYSDRA 63
            ::|.:.:|:.:.||:.|.|     |:|..|    :|.|    ||||.:.:.....||||:...:.
  Rat     1 MKLNILLLLCVVGLSQADR-----EKIYNG----VECVKNSQPWQVGLFHGKYLRCGGVLVDRKW 56

  Fly    64 ILTAAHCLSNVTVTDLSVRAGSSYWSK---GGQVLKVLKTIAHPKYVPKLYN-PYDIAVLILEAP 124
            :||||||...     ..||.|....||   ..|:.....:|.||.|.....| .:|:.:|.|..|
  Rat    57 VLTAAHCSGK-----YMVRLGEHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLLRLNRP 116

  Fly   125 LRLGGTVKKIPLAEQTPVAGTIVLTSGWGYTRENSSFLW-PI---LQGVHVAILNRTDCLKAYKH 185
            :.|...|:.:.|.......|.....||||.|.:.    | |.   ||.:.::|::...| :|...
  Rat   117 ISLTYAVRPVALPSSCAPTGAKCHISGWGTTNKP----WDPFPDRLQCLDLSIVSNETC-RAVFP 176

  Fly   186 VNITIDMICADGQRW-DTCQGDSGGPLIETTKGGHRQLIGMVSWGD--GCGTN--PGVYEDIAFF 245
            ..:|.:|:||.|:.. |.|||||||||:   .||..|  |:||||.  .||..  ||||..:..:
  Rat   177 GRVTENMLCAGGEAGKDACQGDSGGPLV---CGGVLQ--GLVSWGSVGPCGQKGIPGVYTKVCKY 236

  Fly   246 HNWIKYTVKKN 256
            .:||:..::.|
  Rat   237 TDWIRVVIRNN 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	78/237 (33%)
CG31681	NP_722789.1	Tryp_SPc	29..250	CDD:238113	79/237 (33%)
Klk12	XP_008757573.1	Tryp_SPc	21..240	CDD:214473	78/237 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010