Protein Alignment CG31681 and HABP2

DIOPT Version :10

• Sequence 1: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_004123.1
• Gene: HABP2 / 3026
• HGNCID: 4798
• Length: 560
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 94/291 - (32%)
• Similarity: 126/291 - (43%)
• Gaps: 63/291 - (21%)

  Fly    17 ACAAR-IPGPEE--------------------------RIVGGSYIPIEYVPWQVSVQNN----- 49
            ||:|: :..|||                          ||.||........|||.|:|::
Human   275 ACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTI 339

  Fly    50 SL---HCCGGVIYSDRAILTAAHCLSNVTVTDLSVRAGSSYWSK---GGQVLKVLKTIAHPKYVP 108
            |:   |.|||.:.....:|||||| :::....|.|..|.....|   ..|..:|.|...:..|..
Human   340 SMPQGHFCGGALIHPCWVLTAAHC-TDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNE 403

  Fly   109 KLYNPY-DIAVLILEAPLRLGG-------TVKKIPLAEQTPVAGTIVLTSGWGYTRENSSFLWPI 165
            :...|: |||:|.|:.   :.|       .||.:.|.:.:..:|:....||||.|........
Human   404 RDEIPHNDIALLKLKP---VDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQ-- 463

  Fly   166 LQGVHVAILNRTDC--LKAYKHVNITIDMICA-----DGQRWDTCQGDSGGPLIETTKGGHRQLI 223
            |....|.::..|.|  .:.|.|: |...||||     .||  ||||||||||| ...|.|...:.
Human   464 LLDAKVKLIANTLCNSRQLYDHM-IDDSMICAGNLQKPGQ--DTCQGDSGGPL-TCEKDGTYYVY 524

  Fly   224 GMVSWGDGCGTNPGVYEDIAFFHNWIKYTVK 254
            |:||||..||..||||..:..|.||||.|:|
Human   525 GIVSWGLECGKRPGVYTQVTKFLNWIKATIK 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	83/246 (34%)
HABP2	NP_004123.1	EGF	77..106	CDD:394967
		KR	191..277	CDD:238056	1/1 (100%)
		Tryp_SPc	314..553	CDD:238113	85/248 (34%)