Protein Alignment CG31681 and KLK5

DIOPT Version :10

• Sequence 1: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 88/254 - (34%)
• Similarity: 128/254 - (50%)
• Gaps: 24/254 - (9%)

  Fly    14 AGLACAARIPGPEERIVGGSYIPIEYVPWQVS--VQNNSLHCCGGVIYSDRAILTAAHCLSNVTV 76
            ||....||......||:.||...:...|||.:  ::.|.|: ||.|:...:.:||||||...|
Human    52 AGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHCRKKV-- 113

  Fly    77 TDLSVRAG----SSYWSKGGQVLKVLKTIAHPKYV-PKLYNPYDIAVLILEAPLRLGGTVKKIPL 136
              ..||.|    |..:..|.|:.:.:|:|.||.|. |...|  |:.::.|...:|....|:.|.:
Human   114 --FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSN--DLMLIKLNRRIRPTKDVRPINV 174

  Fly   137 AEQTPVAGTIVLTSGWGYTRENSSFLWPILQGVHVAILNRTDCLKAYKHVNITIDMICA-DGQRW 200
            :...|.|||..|.||||.|:........:||.:::::|::..|..||.. .|...|.|| |....
Human   175 SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR-QIDDTMFCAGDKAGR 238

  Fly   201 DTCQGDSGGPLIETTKGGHRQLIGMVSWGD-GCG--TNPGVYEDIAFFHNWIKYTVKKN 256
            |:||||||||::     .:..|.|:||||| .|.  ..||||.::..|..||:.|::.|
Human   239 DSCQGDSGGPVV-----CNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	80/231 (35%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/15 (33%)
		Tryp_SPc	66..285	CDD:214473	80/231 (35%)