Protein Alignment CG31681 and F12

DIOPT Version :10

• Sequence 1: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 84/269 - (31%)
• Similarity: 121/269 - (44%)
• Gaps: 42/269 - (15%)

  Fly    16 LACAARIP---GPEERIVGG--------SYIPIEYVPWQVSVQNNSLHCCGGVIYSDRAILTAAH 69
            |:|..|:.   ....|:|||        .||...|  |..|.       |.|.:.:...:|||||
Human   357 LSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALY--WGHSF-------CAGSLIAPCWVLTAAH 412

  Fly    70 CLSN-VTVTDLSVRAGS---SYWSKGGQVLKVLKTIAHPKYVPKLYNPYDIAVLILE-----APL 125
            ||.: ....||:|..|.   ::..:..|.|.|.....|..:.|..|. :|:|:|.|:     :..
Human   413 CLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQ-HDLALLRLQEDADGSCA 476

  Fly   126 RLGGTVKKI--PLAEQTPVAGTIVLTSGWGYTRENSSFLWPILQGVHVAILNRTDCLKAYKH-VN 187
            .|...|:.:  |.....|...|:...:|||:..|.:......||...|..|:...|.....| .:
Human   477 LLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSS 541

  Fly   188 ITIDMICA---DGQRWDTCQGDSGGPLIETTKGGHRQLI--GMVSWGDGCG--TNPGVYEDIAFF 245
            |...|:||   :|.. |.|||||||||:...:...|:|.  |::|||.|||  ..||||.|:|::
Human   542 ILPGMLCAGFLEGGT-DACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYY 605

  Fly   246 HNWIK-YTV 253
            ..||: :||
Human   606 LAWIREHTV 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	77/247 (31%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		1/1 (100%)
		Tryp_SPc	373..612	CDD:238113	78/249 (31%)