Protein Alignment CG31681 and PRSS21

DIOPT Version :10

• Sequence 1: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 102/281 - (36%)
• Similarity: 136/281 - (48%)
• Gaps: 40/281 - (14%)

  Fly     5 LLLSILVSIAGLAC-----AARIPGP------EERIVGGSYIPIEYVPWQVSVQNNSLHCCGGVI 58
            |||::|::.|||..     ||.:.||      ..|||||....:...|||.|::....|.||..:
Human     7 LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHVCGVSL 71

  Fly    59 YSDRAILTAAHCLSNVTVTDLSVRAG-----------SSYWSKGGQVLK--VLKTIAHPKYVPKL 110
            .|.|..||||||..  |.:|||..:|           .|:||......:  |......|:|:..
Human    72 LSHRWALTAAHCFE--TYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGN- 133

  Fly   111 YNPYDIAVLILEAPLRLGGTVKKIPLAEQT--PVAGTIVLTSGWGYTRENSSFLWP-ILQGVHVA 172
             :|||||::.|.||:.....::.|.|...|  ....|....:||||.:|:.:...| .||.|.||
Human   134 -SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVA 197

  Fly   173 ILNRTDC----LKAYKHVNITIDMICADGQRW--DTCQGDSGGPLIETTKGGHRQLIGMVSWGDG 231
            |:|.:.|    ||.....:|..||:||...:.  |.|.||||||| ...|.|....||:||||.|
Human   198 IINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPL-ACNKNGLWYQIGVVSWGVG 261

  Fly   232 CG--TNPGVYEDIAFFHNWIK 250
            ||  ..||||.:|:....||:
Human   262 CGRPNRPGVYTNISHHFEWIQ 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	89/244 (36%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	90/246 (37%)