DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31674 and Grhpr

DIOPT Version :9

Sequence 1:	NP_001286111.1	Gene:	CG31674 / 318878	FlyBaseID:	FBgn0051674	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_001107226.1	Gene:	Grhpr / 680021	RGDID:	1308851	Length:	335	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	135/311 - (43%)
Similarity:	193/311 - (62%)	Gaps:	3/311 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VPPEGIEILKE--QCEILQVINEPPKNRPEILEKIRGAHAVIWGGRDILNAEILDAAGPQLKAVS 78
            :|.:|...|.:  .||:.|..::.|....::.:.:.||:.::....|.::.::|||||..|:.:|
  Rat    22 LPAQGRAALAQATDCEVEQWNSDDPIPSKDLEQGVAGAYGLLCRLSDRVDKKLLDAAGANLRVIS 86

  Fly    79 TMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAARRFQEGRRKIDSDKWDKDHLN 143
            |:|.|::::.:.|:|||||.:|.||.:||.|.|:|.|.||:...||..|...::.:..|......
  Rat    87 TLSVGVDHLALDEIKKRGIRVGYTPGVLTDATAELAVSLLLTTCRRLPEAIEEVKNGGWSSWSPL 151

  Fly   144 WMLGQDIRDSTVGFYGFGGIGQAVAKRLMGFDIKRMLYTTRNRVSQDIEERFNAKKVDFETLLAE 208
            ||.|..:.:||||..|.|.||||:|:||..|.::|.|||.|....|:..| |.|:.|....|.||
  Rat   152 WMCGYGLSESTVGIVGLGRIGQAIARRLKPFGVQRFLYTGRQPRPQEAAE-FQAEFVPIAQLAAE 215

  Fly   209 SDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDP 273
            |||::::..||..|.||.|...|.|||.|||.:|:.||.:|||:|||:||.|.:|.||||||..|
  Rat   216 SDFIVVSCSLTPATRGLCNKDFFQKMKNTAVFINISRGDVVNQEDLYQALASGQIAAAGLDVTTP 280

  Fly   274 EPLPSNDKLLTLDNVVVTPHVGYATRRTRVDAANLASRNVLKGLAGEPMLS 324
            ||||.:..||||.|.|:.||:|.||.:||...:.||:.|:|.||.||||.|
  Rat   281 EPLPPSHPLLTLKNCVILPHIGSATYKTRNTMSLLAANNLLAGLRGEPMPS 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31674	NP_001286111.1	GDH	8..319	CDD:240626	130/304 (43%)
CG31674	NP_001286111.1	LdhA	9..321	CDD:223980	131/306 (43%)
Grhpr	NP_001107226.1	GDH	14..326	CDD:240626	130/304 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53501
OrthoDB	1	1.010	-	-		D1378766at2759
OrthoFinder	1	1.000	-	-		FOG0000836
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100397
Panther	1	1.100	-	-	O	PTHR10996
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X646
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.760