DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31674 and SPAC186.02c

DIOPT Version :9

Sequence 1:	NP_001286111.1	Gene:	CG31674 / 318878	FlyBaseID:	FBgn0051674	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_595020.1	Gene:	SPAC186.02c / 2542495	PomBaseID:	SPAC186.02c	Length:	332	Species:	Schizosaccharomyces pombe

Alignment Length:	256	Identity:	74/256 - (28%)
Similarity:	124/256 - (48%)	Gaps:	25/256 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 DILNAEILDA-AGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAAR 123
            |.::|:.|.| |...:|.|:....|.|||::....:..|.:...|:....||::.|||||::..|
pombe    54 DQVDADTLKALAENGVKLVALRCGGYNNVNLKAASEYKITVVHVPSYSPFAVSEFTVGLLLSLNR 118

  Fly   124 RFQEGRRKIDSDKWDKDHLNWMLGQDIRDSTVGFYGFGGIGQAVAKRL-MGFDIKRMLYTTRNRV 187
            :......::..|.:   ::..:||.||...|||..|.|.||..|||.. |||....:.|.    :
pombe   119 KIHRAYVRVREDDF---NIVGLLGCDIHGKTVGVIGTGKIGSNVAKCFKMGFGCDVLAYD----I 176

  Fly   188 SQDIE-ERFNAKKVDFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQ 251
            :.|.: |.:..:.|:...:|.::|||.:..|||..|..:.|:.....||:...:||..||.:::.
pombe   177 NPDKKLENYGVQFVEQNEVLKKADFLCLHCPLTPSTTHIVNSDSLALMKKGVTIVNTSRGGLIDT 241

  Fly   252 DDLYEALKSNRIFAAGLDVMDPE------PLPSND--------KLLTLDNVVVTPHVGYAT 298
            ..|.:|:.|.::....:||.:.|      .| ||:        :|:...||:||.|..:.|
pombe   242 KALVDAIDSGQVGGCAIDVYEGERNLFYKDL-SNEVIKDSTFQRLVNFPNVLVTSHQAFFT 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31674	NP_001286111.1	GDH	8..319	CDD:240626	74/256 (29%)
CG31674	NP_001286111.1	LdhA	9..321	CDD:223980	74/256 (29%)
SPAC186.02c	NP_595020.1	LdhA	1..322	CDD:223980	74/256 (29%)
SPAC186.02c	NP_595020.1	LDH_like_2	1..319	CDD:240659	74/256 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53501
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880