DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31674 and SPCC364.07

DIOPT Version :9

Sequence 1:	NP_001286111.1	Gene:	CG31674 / 318878	FlyBaseID:	FBgn0051674	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_587837.1	Gene:	SPCC364.07 / 2539490	PomBaseID:	SPCC364.07	Length:	466	Species:	Schizosaccharomyces pombe

Alignment Length:	345	Identity:	94/345 - (27%)
Similarity:	162/345 - (46%)	Gaps:	51/345 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TTKPF-----KVLIAHTDVPPEGIEILKE---QCEILQVINEPPKNRPEILEKIRGAHAVIWGGR 59
            |.|||     |:|:.. :|....:..||:   |.|.|:.    ..:..:::|||:|.||:....:
pombe    47 TLKPFASEDIKILLLE-NVNQSALSNLKDEGYQVEFLKT----SMSEDDLVEKIKGVHAIGIRSK 106

  Fly    60 DILNAEILDAAGPQLKAVSTMSSGINNVDVPELKKRGIPLGSTPAMLTVAVADLTVGLLIAAARR 124
            ..|...:|:|| ..|..:.....|.|.||:....:|||.:.::|...:.:||:|.:|.:|:.||:
pombe   107 TRLTRRVLEAA-DSLIVIGCFCIGTNQVDLDFAAERGIAVFNSPYANSRSVAELVIGYIISLARQ 170

  Fly   125 FQEGRRKIDSDKWDKDHLN-WMLGQDIRDSTVGFYGFGGIGQ--AVAKRLMGFDIKRMLYTTRNR 186
            ..:...::...:|:|.... |    :||..|:|..|:|.||.  :|....||..:
pombe   171 VGDRSLELHRGEWNKVSSGCW----EIRGKTLGIIGYGHIGSQLSVLAEAMGLHV---------- 221

  Fly   187 VSQDIEERF---NAKKV-DFETLLAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGK 247
            |..||....   :||:: ....||..:||:.:..|.:.||..:.::..|..|||.:.|:|..||.
pombe   222 VYYDILPIMPLGSAKQLSSLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGT 286

  Fly   248 IVNQDDLYEALKSNRIFAAGLDVMDPEPLPS-NDK-----------LLTLDNVVVTPHVGYATRR 300
            :|:...|.:|.||.:|..|.:||...||..: .||           |....|:::|||:|.:|..
pombe   287 VVDIPALVDASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTEE 351

  Fly   301 TR----VDAANLASRNVLKG 316
            .:    ::.:...:|.:.:|
pombe   352 AQYNIGIEVSEALTRYINEG 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31674	NP_001286111.1	GDH	8..319	CDD:240626	90/335 (27%)
CG31674	NP_001286111.1	LdhA	9..321	CDD:223980	89/334 (27%)
SPCC364.07	NP_587837.1	PRK11790	54..466	CDD:236985	90/338 (27%)
		PGDH_3	56..367	CDD:240653	88/330 (27%)
		ACT_3PGDH	396..465	CDD:153173
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53501
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880