DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and ERF2

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_013347.1	Gene:	ERF2 / 850947	SGDID:	S000004236	Length:	359	Species:	Saccharomyces cerevisiae

Alignment Length:	254	Identity:	69/254 - (27%)
Similarity:	113/254 - (44%)	Gaps:	48/254 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLTTFLFFFYPCQFYVKSHPWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDEDCEEELRAPL 85
            :|..|.::|           ||:         .||:|......|||::|:...........:.|
Yeast   108 VLVIFFYYF-----------WVI---------TLASFIRTATSDPGVLPRNIHLSQLRNNYQIP- 151

  Fly    86 YKNAEINGIT----------VKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRN 140
              ....|.||          :.:|:|.:|:.:||||.||||.||.|:...||||.|||||||:||
Yeast   152 --QEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRN 214

  Fly   141 YRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIPIFGLTGFHMVL 205
            ||||..||:...:..:.:.:.|.:::.:.....:| .|:..::|......|..|....| :|:.:
Yeast   215 YRFFLIFLLGAILSSVILLTNCAIHIARESGGPRD-CPVAILLLCYAGLTLWYPAILFT-YHIFM 277

  Fly   206 VSRGRTTNEQVTGKFKGGYNP-----------FSRGCW-HNCCYTQFGPQYPSLLNPKK 252
            ....:||.|.:.| .....||           :::|.: .|..:....|:.||.::.:|
Yeast   278 AGNQQTTREFLKG-IGSKKNPVFHRVVKEENIYNKGSFLKNMGHLMLEPRGPSFVSARK 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	46/134 (34%)
ERF2	NP_013347.1	COG5273	47..359	CDD:227598	69/254 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1540
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	1	1.000	-	-		otm46915
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R405
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840