Protein Alignment Zdhhc8 and ZDHHC18

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_115659.1
• Gene: ZDHHC18 / 84243
• HGNCID: 20712
• Length: 388
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 108/285 - (37%)
• Similarity: 159/285 - (55%)
• Gaps: 43/285 - (15%)

  Fly    18 IVLLLTTFLFFFYPCQFYVK----SHPWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDEDCE 78
            :::|.||.|||.:.|.:..:    :.|.:.|   ::.|||::.....:|.||||:|:|:..|...
Human    99 LLILTTTGLFFVFDCPYLARKLTLAIPIIAA---ILFFFVMSCLLQTSFTDPGILPRATVCEAAA 160

  Fly    79 EELR-----------APLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWV 132
            .|.:           .|..:...|||..||:|:|.|||.:||||.||||||::|:|.||||||||
Human   161 LEKQIDNTGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWV 225

  Fly   133 NNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKI-------MPNIKDTAPIVAIILMGLVTI 190
            .||:||||||||:.|::|||.....||: |:|..|.:       :..:|:|...|..:::...:|
Human   226 GNCVGRRNYRFFYAFILSLSFLTAFIFA-CVVTHLTLRAQGSNFLSTLKETPASVLELVICFFSI 289

  Fly   191 LAIPIFGLTGFHMVLVSRGRTTNEQVTGKF---KGG---YNPFS-RGCWHNCCYTQFGPQYPSLL 248
            .:  |.||:|||..||:...||||.:.|.:   :||   .||:| :....|||....||..|||:
Human   290 WS--ILGLSGFHTYLVASNLTTNEDIKGSWSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLI 352

  Fly   249 NPKKYASRRSQVQNQAI--STICND 271
            :      ||..||:..:  |.|.:|
Human   353 D------RRGFVQSDTVLPSPIRSD 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	60/126 (48%)
ZDHHC18	NP_115659.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..67
		DHHC	191..314	CDD:396215	60/125 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..388		3/8 (38%)