Protein Alignment Zdhhc8 and zdhhc5b

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001429732.1
• Gene: zdhhc5b / 792560
• ZFINID: ZDB-GENE-101117-1
• Length: 718
• Species: Danio rerio
• Alignment Length: 721
• Identity: 218/721 - (30%)
• Similarity: 299/721 - (41%)
• Gaps: 188/721 - (26%)

  Fly     8 TRYIPATFAWIVLLLTTFLFFFYPCQFYVKSHPW--------VLAYQGVITFFVLANFTLATFMD 64
            :||:|.:.|...|:..|.||..:.|       ||        :..|..|:..|.||||.:|||||
Zfish    23 SRYVPVSAATAFLVGATTLFLCFTC-------PWLSEKFSSFIPLYNVVVFLFTLANFCMATFMD 80

  Fly    65 PGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHC 129
            ||:.|:|..|||.|::.||||||..|:.||.|:||||.||:|||||||||||||::|:|.|||||
Zfish    81 PGVFPRAEEDEDKEDDFRAPLYKTVEVRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEEFDHHC 145

  Fly   130 PWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIP 194
            |||||||||||||:||.||:||::|::.:|...|:|:|.....:......|.:.:|.:..:..:|
Zfish   146 PWVNNCIGRRNYRYFFLFLLSLTVHIMDVFGFSLLYILHHTKQLDLVQSGVTMAVMCVAGLFFVP 210

  Fly   195 IFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASRRSQ 259
            :.||||||:|||:|||||||||||||:||.|||:.||:.|..:.....|.|      :|..|..:
Zfish   211 VAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTHGCFKNIAHVLCSSQAP------RYLGRLRK 269

  Fly   260 VQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSFYDASREKR 324
            .|                                              :||..| .|......:.
Zfish   270 PQ----------------------------------------------SVQVQP-PFLRPPLSEA 287

  Fly   325 GIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPPPA------------SQSQDCE--- 374
            .:..|..   .||..|...|..:       .|...||.:|||.            :|:::|.
Zfish   288 QLAAKVL---DNGIQQSKSSLEI-------MESQSTDADPPPPPKPEHRYPGLPHTQNEECSLLT 342

  Fly   375 ---PTPPLQRHNSSSFYLPQVSDSGGLNGSVST------GGGGGGDSPR-HMRLYHP--RHSPHA 427
               |||.|.:      |.|..| |.|.|.:.||      .|....:||. .:....|  |..|..
Zfish   343 EAPPTPSLYK------YRPAYS-SPGKNHTASTHSSKMSRGNSMTESPSVPVTTGQPSYRSDPSL 400

  Fly   428 RPRGLDPQRGYTSDALSPDHPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSATTTATPTMQ 492
            ..||....||......|....:| |....|.:...........:|||..:.:.|||.|..
Zfish   401 SSRGAAGCRGGAEGGRSGSGGLG-GASAFGGRSYPSFTDTLLQSAAASCSSSLRSAHTAH----- 459

  Fly   493 QRIKPLGVATPLVMASPVRRSNPGTPTQPRR--------------PDFIGLNAQAVAQQ------ 537
               ..||   ||:.......|......|.|.              |:|     ::.|.:
Zfish   460 ---NALG---PLISEGTTSTSYKSLANQTRNGSLSYESLLTPSESPEF-----ESAAHELSPPRP 513

  Fly   538 QQQQQQAAAAAAAAYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQ 602
            ......:.||.||....|||         |.:..||::..||.....::....:..|:.......
Zfish   514 HPPHSLSTAAGAAPILGYTS---------PFLSAQQREGSLQACPAPLRPSPNRAFLRPISSPPS 569

  Fly   603 QAAVHAAH------------PQHAALAQA-AYGGSPQRRFLSEGELVRQ--GAGGGVAGGELSYA 652
            :|...:..            |.|..|.:: :|||.        .||..:  .:|||.       :
Zfish   570 RAPPLSPRARSLGSPPPGPAPGHTPLGKSMSYGGG--------AELQHRPSSSGGGT-------S 619

  Fly   653 RSNNTV 658
            ..||||
Zfish   620 MPNNTV 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	71/119 (60%)
zdhhc5b	NP_001429732.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..419		31/126 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	490..522		3/36 (8%)