DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zdhhc8 and zdhhc15b

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001071249.1	Gene:	zdhhc15b / 777734	ZFINID:	ZDB-GENE-061110-106	Length:	332	Species:	Danio rerio

Alignment Length:	252	Identity:	67/252 - (26%)
Similarity:	110/252 - (43%)	Gaps:	49/252 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FAWI-------VLLLTTFLFFFYPCQFYVKSHPWVLAYQGVITFFVLANFTLATFMDPGIIPKAS 72
            |:||       |:|.:.:.:.|..|...:.::...:.|  ::.|.|.......|:......|.::
Zfish    14 FSWIPVIIISSVVLWSYYAYVFELCFVTLSNNLGRVTY--LLIFHVCFIMFCWTYWKAIFTPPST 76

  Fly    73 PDE------------DCEEE------------LRAPLYKNAEINGITVKMKWCVTCKFYRPPRCS 113
            |.:            :.||.            .:.|::..|:...|    ::|..|:..:|.||.
Zfish    77 PTKKFHLSYTDKERYEMEERPEVQKQILVDIAKKLPIFTRAQSGAI----RFCDRCQVIKPDRCH 137

  Fly   114 HCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKI----MPNIK 174
            |||||..|:...||||||||||:|..||:||..||....|:.:.|.|....|.||.    :||
Zfish   138 HCSVCETCVLKMDHHCPWVNNCVGFSNYKFFLLFLSYSMIYCVFIASTVFQYFLKFWVGDLPN-- 200

  Fly   175 DTAPIVAIILMGLVTILAIPIFGLTGFHMVLVSRGRTTNEQVT------GKFKGGYN 225
            ..|....:.|:.:..:..:.:..|.|:|..||::.|:|.|..:      |..:.|:|
Zfish   201 GPAKFHVLFLLFVALMFFVSLMFLFGYHCWLVAKNRSTLEAFSPPVFQNGPDRNGFN 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	47/134 (35%)
zdhhc15b	NP_001071249.1	zf-DHHC	16..292	CDD:303066	66/250 (26%)
zdhhc15b	NP_001071249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810