DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and zdhhc3b

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001071225.1	Gene:	zdhhc3b / 777709	ZFINID:	ZDB-GENE-061110-19	Length:	300	Species:	Danio rerio

Alignment Length:	217	Identity:	59/217 - (27%)
Similarity:	92/217 - (42%)	Gaps:	47/217 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ATFAWIVLLLTTFLFFF---YPCQFYVKSHPWVLAYQGV-------ITFFVLANFTLATFMDPGI 67
            |...|:::|...|:..|   .|.:        .|.|..:       :.|..||:...|...|||.
Zfish    49 AVITWLLVLYAEFVVVFVMLLPAR--------SLLYSFINGALFNSLAFLALASHLRAMCTDPGA 105

  Fly    68 IPKASPDEDCEEELRAP----LYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHH 128
            :||.:..::..|.|:..    :||             |..|...:|.|..|||||..||:..|||
Zfish   106 VPKGNATKEFIESLQLKPGQVVYK-------------CPKCCSIKPDRAHHCSVCKRCIKKMDHH 157

  Fly   129 CPWVNNCIGRRNYRFFFFF---LVSLSIHMLSIFSLCLVYVLK----IMPNIKDTAPIVAIILMG 186
            |||||||:|..|.::|..|   :..:|:|.|.:.:...|:..:    ...:....|.::.:||:.
Zfish   158 CPWVNNCVGENNQKYFVLFTMYIALISLHALLMVAFHFVFCFEEDWAKCSSFSPPATVILLILLC 222

  Fly   187 ----LVTILAIPIFGLTGFHMV 204
                |..|....:|| |..|.:
Zfish   223 FEALLFLIFTAVMFG-TQVHSI 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	38/122 (31%)
zdhhc3b	NP_001071225.1	zf-DHHC	130..256	CDD:279823	38/115 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810