Protein Alignment Zdhhc8 and Zdhhc1

DIOPT Version :9

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001365935.1
• Gene: Zdhhc1 / 70796
• MGIID: 1918046
• Length: 484
• Species: Mus musculus
• Alignment Length: 563
• Identity: 123/563 - (21%)
• Similarity: 183/563 - (32%)
• Gaps: 197/563 - (34%)

  Fly    16 AWIVLLLTTFLFFFYPCQFYV----KSHPWV---LAYQGVITFFVLANFTLATFMDPGIIPKASP 73
            ||::.|      ||....|.|    ..|.||   .|..|.|....|.....|..:||.
Mouse    52 AWLLYL------FFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPA------- 103

  Fly    74 DEDCEEELRA---PLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNC 135
            |.:..::..:   |::..:: :...::...|..|......|..|||.||.|:..|||||.|:|||
Mouse   104 DANVRDKSYSGPLPIFNRSQ-HAHVIEDLHCNLCDVDVSARSKHCSACNKCVCGFDHHCKWLNNC 167

  Fly   136 IGRRNYRFFFFFLVSLSIHMLSIFSLCLV--YV----------------LKIMPNIKD------- 175
            :|.||||   .||.|::..:|.:..|.||  ||                .:::.|..|
Mouse   168 VGERNYR---LFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNQHFEVLKNHTDVWFVFLP 229

  Fly   176 TAPI-----------VAIILMGLVTILAIPIFG-LTGFHMVLVSRGRTTNEQVTGKFKGGYNPFS 228
            .||:           ..:||:||   |:..:.| |..||:.|:
Mouse   230 AAPVETQAPAILALAALLILLGL---LSTALLGHLLCFHIYLM---------------------- 269

  Fly   229 RGCWHNCCYTQFGPQYPSLLNPKKYASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSG 293
               ||.....::..|:       :.|....:...:..|.....||.|:
Mouse   270 ---WHKLTTYEYIVQH-------RPAQEAKETHKELESCPRKVRSIQE----------------- 307

  Fly   294 GGGGVGSGGGMRGTAVQYSPRSFYDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECS 358
                           :::..|:|.....|..| |.:|.....|                |.:..:
Mouse   308 ---------------MEFYMRTFSHVRPEPSG-QARTAALNAN----------------PSQFLA 340

  Fly   359 DTDLEPPPASQSQDCEPTPPL---QRHNSSSFY-LPQVSDSGGLNGSVSTGGGGGGDSPRHMRLY 419
            ......||...|.|....||.   |:......| ||:   ||.|:              |.:.|
Mouse   341 TQGQVEPPLPSSSDTLALPPRIQPQKKRKRRVYRLPR---SGVLD--------------RELPL- 387

  Fly   420 HPRHSPHARPRGLDPQRGYTSD---ALSPDHPVG-YGVGVNGSQQQQQ-----QALAAAAAAAAV 475
                 |..|..|...:|..:|.   :.||.|..| .|...:.|.:..:     |....:||..|.
Mouse   388 -----PRLRETGTPSRRSSSSSDSTSASPVHAGGSAGAYYSASAESMEEIPVAQTRLGSAALGAP 447

  Fly   476 AAQNQRSATTTATPTMQQRIKPLGVATPLVMASPVRRSNPGTP 518
            .|:.:.|..     .:|.|       :|.|..|| ....||||
Mouse   448 GARGRESGL-----ALQAR-------SPAVFVSP-SSGEPGTP 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	46/161 (29%)
Zdhhc1	NP_001365935.1	Mediates interaction with STING1. /evidence=ECO:0000250|UniProtKB:Q8WTX9	1..268		64/235 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		DHHC	126..281	CDD:396215	48/185 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..415		23/96 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..484		13/47 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910