DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and Zdhhc24

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_081752.2	Gene:	Zdhhc24 / 70605	MGIID:	1917855	Length:	284	Species:	Mus musculus

Alignment Length:	235	Identity:	60/235 - (25%)
Similarity:	89/235 - (37%)	Gaps:	56/235 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 AYQGVITFFVLANFTLATFMDPGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKW--CVTCKF 106
            |||   ...:|.|..|....||.|                   :...:.|..:...|  |..|:.
Mouse    59 AYQ---LLNLLGNVVLFLRSDPSI-------------------RGVMLAGRGLGQGWAYCYQCQS 101

  Fly   107 YRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLV---SLSIH-----------MLS 157
            ..|||..|||.|..||...||||..:..|:|..|||.|...|:   .:.:|           :|.
Mouse   102 QVPPRSGHCSACRVCILRRDHHCRLLGCCVGFHNYRPFLCLLLHSAGVLLHISVLLGPALSALLQ 166

  Fly   158 IFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIPIFG--LTG----FHMVLVSRGRTTNEQV 216
            ..|......|.::|.:......|::....|..::...:.|  |.|    ||.:|:.||:||.|
Mouse   167 AHSALYTVALLLLPWLMLLTGKVSLAQFALAFVVDTCVAGALLCGAGLLFHGMLLLRGQTTWE-- 229

  Fly   217 TGKFKGGYNPFSRGCWHNCCYTQFGPQ------YPSLLNP 250
               :..|::.:..|..|| .....||:      :|.|.:|
Mouse   230 ---WARGHHCYDLGTCHN-LQAALGPRWALVWFWPFLASP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	41/146 (28%)
Zdhhc24	NP_081752.2	zf-DHHC	95..232	CDD:279823	40/141 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810