DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	187	Identity:	51/187 - (27%)
Similarity:	79/187 - (42%)	Gaps:	53/187 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GVITFFVLANFTL--------ATFMDPGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVT 103
            |.:.|.:|.|:|:        |.|..||.:|:....|..::               ::.:::|..
Mouse    54 GSVNFIMLINWTVMILYNYFNAMFAGPGFVPRGWKPEKSQD---------------SMYLQYCKV 103

  Fly   104 CKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSI---HMLSIFSLCL-- 163
            |:.|:.||..||..||.|:...||||||:|||.|.:|:..|..||:...:   |...||.:.:
Mouse   104 CQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYT 168

  Fly   164 -VY--------VLKIMPNI--KDTAPIVAIILMGLVTILAIPIFGLTGFHMVLVSRG 209
             :|        .:||..:.  :|..|||.              |||..|...|.:.|
Mouse   169 QLYNRLSFGWNTVKIDMSAARRDPPPIVP--------------FGLAAFAATLFALG 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	40/132 (30%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	40/131 (31%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900