Protein Alignment Zdhhc8 and zdhhc5a

DIOPT Version :9

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_005160301.1
• Gene: zdhhc5a / 571795
• ZFINID: ZDB-GENE-090312-92
• Length: 760
• Species: Danio rerio
• Alignment Length: 936
• Identity: 256/936 - (27%)
• Similarity: 356/936 - (38%)
• Gaps: 348/936 - (37%)

  Fly     8 TRYIPATFAWIVLLLTTFLFFFYPCQFYVKSHPW--------VLAYQGVITFFVLANFTLATFMD 64
            :||:|.:.|...|:.:|.|||.:.|       ||        |..|.||:..||||||.:|||||
Zfish    29 SRYVPVSAATAFLVGSTTLFFCFTC-------PWLSEQFSVAVPIYNGVMFMFVLANFCMATFMD 86

  Fly    65 PGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHC 129
            |||.|:|..|||.|::.||||||..||.||.|:||||.||:|||||||||||||::|:|.|||||
Zfish    87 PGIFPRAEEDEDKEDDFRAPLYKTVEIRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEDFDHHC 151

  Fly   130 PWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIP 194
            |||||||||||||:||.||:||:.|::.:|...|:::|.....:......|.:.:|.:..:..||
Zfish   152 PWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLFILYHTQQLDRVHSAVTMAVMCVAGLFFIP 216

  Fly   195 IFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASR--- 256
            :.||||||:|||:|||||||||||||:||.|||:.||..|..:.....|.|..|..|:.|..
Zfish   217 VAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCLRNVSHVLCSSQAPRYLGRKRKAQTVSV 281

  Fly   257 -----RSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSF 316
                 |.|:....::....|                              .|::|
Zfish   282 QPPFLRPQLTEAQLAAKVLD------------------------------NGIQG---------- 306

  Fly   317 YDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPP---------------P 366
             |..|.|..:::                          .|....|.|||               |
Zfish   307 -DLHRSKSSLEM--------------------------MESQSADAEPPPPPKPELRYPGLSRGP 344

  Fly   367 ASQSQD------CEPTP-----------PLQRHNS-----------------SSFYLPQVS---- 393
            |..|::      ..|||           |.:.|.:                 ||..|.|.|
Zfish   345 AGHSEESSLLNKAPPTPTMFKYRPTYSSPGKNHTALTHAYANQMSRGDSLKESSSSLLQSSQQPG 409

  Fly   394 ----------DSGGL--NGSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDALSPD 446
                      :.||.  :|:..||||.||                      .|..|..
Zfish   410 YRSEPSLDGREGGGAERSGAERTGGGPGG----------------------PPGSGIP------- 445

  Fly   447 HPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSA------TTTATPTMQQRIKPL------- 498
               ||.:|...........:.|..|:.:.:.::..:|      |:|:..::..:..|.
Zfish   446 ---GYSLGGRSYPSFSDPTVLAERASRSSSVRSTHNAPPSEATTSTSYKSLANQTPPQAARNGSL 507

  Fly   499 ---GVATP-----LVMASPVRRSNPGTPTQPRRPDFIG-----LNAQAVAQQQQQQQQAAAAAAA 550
               .:.||     ...|:|  ..:||.|..|    .:|     |:||...|::.:..|..|:::|
Zfish   508 SYDSLLTPSESPDFESAAP--EMSPGRPRTP----VVGYSSPFLSAQIAHQREAELHQPVASSSA 566

  Fly   551 -------AYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHA 608
                   |.:...||.||..|     ::::::||...|   .||....               |.
Zfish   567 LMASPQHAVFLRGSGSPPVPP-----ERERERLLHDSQ---AQHHHHH---------------HH 608

  Fly   609 AHPQHAALAQAAYGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGSPQRGVY 673
            .|..|          .|.|                       ::|.....|     :|.||.. |
Zfish   609 HHHHH----------RPPR-----------------------FSRPPLLSD-----SGPPQPS-Y 634

  Fly   674 MWKDTSPGFTNNAGQQQQQQQQAQQVVSSGIGSSAGTLSSSGAAAGVMPH-----AQYMTAGGGA 733
            .::..|...|:.........          :|.|   ||.|.|||..|.:     |....||||
Zfish   635 PYRTRSTDTTHPPRSPHPPP----------LGKS---LSYSSAAAAEMQYRLVRKASASVAGGG- 685

  Fly   734 HPLIMTHSRLQDYTIQQQQQQQQQQAAAAAAASYHRSN--------PTSPTTMPQVS-------- 782
                          ||..:.:.|.:       ||.|:|        |:|||....||
Zfish   686 --------------IQAPKDEIQMK-------SYSRTNGQPKPSSTPSSPTHPISVSTRPGQAHS 729

  Fly   783 --GAGQSYILRYGGG--GAVGAAGSS 804
              |:.||...:.|||  ...|..|::
Zfish   730 SAGSSQSPAHKPGGGVKKVTGVGGTT 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	74/124 (60%)
zdhhc5a	XP_005160301.1	zf-DHHC	116..241	CDD:279823	74/124 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	185	1.000	Domainoid score	I3310
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2464
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104772
Panther	1	1.100	-	-	LDO	PTHR12349
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R405
SonicParanoid	1	1.000	-	-		X1910
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.000