Protein Alignment Zdhhc8 and zdhhc5a

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_005160301.1
• Gene: zdhhc5a / 571795
• ZFINID: ZDB-GENE-090312-92
• Length: 760
• Species: Danio rerio
• Alignment Length: 944
• Identity: 260/944 - (27%)
• Similarity: 359/944 - (38%)
• Gaps: 349/944 - (36%)

  Fly     8 TRYIPATFAWIVLLLTTFLFFFYPCQFYVKSHPW--------VLAYQGVITFFVLANFTLATFMD 64
            :||:|.:.|...|:.:|.|||.:.|       ||        |..|.||:..||||||.:|||||
Zfish    29 SRYVPVSAATAFLVGSTTLFFCFTC-------PWLSEQFSVAVPIYNGVMFMFVLANFCMATFMD 86

  Fly    65 PGIIPKASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHC 129
            |||.|:|..|||.|::.||||||..||.||.|:||||.||:|||||||||||||::|:|.|||||
Zfish    87 PGIFPRAEEDEDKEDDFRAPLYKTVEIRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEDFDHHC 151

  Fly   130 PWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIP 194
            |||||||||||||:||.||:||:.|::.:|...|:::|.....:......|.:.:|.:..:..||
Zfish   152 PWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLFILYHTQQLDRVHSAVTMAVMCVAGLFFIP 216

  Fly   195 IFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASR--- 256
            :.||||||:|||:|||||||||||||:||.|||:.||..|..:.....|.|..|..|:.|..
Zfish   217 VAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCLRNVSHVLCSSQAPRYLGRKRKAQTVSV 281

  Fly   257 -----RSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSF 316
                 |.|:....::....|                              .|::|
Zfish   282 QPPFLRPQLTEAQLAAKVLD------------------------------NGIQG---------- 306

  Fly   317 YDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPP---------------P 366
             |..|.|..:::                          .|....|.|||               |
Zfish   307 -DLHRSKSSLEM--------------------------MESQSADAEPPPPPKPELRYPGLSRGP 344

  Fly   367 ASQSQD------CEPTP-----------PLQRHNS-----------------SSFYLPQVS---- 393
            |..|::      ..|||           |.:.|.:                 ||..|.|.|
Zfish   345 AGHSEESSLLNKAPPTPTMFKYRPTYSSPGKNHTALTHAYANQMSRGDSLKESSSSLLQSSQQPG 409

  Fly   394 ----------DSGGL--NGSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDALSPD 446
                      :.||.  :|:..||||.||                      .|..|..
Zfish   410 YRSEPSLDGREGGGAERSGAERTGGGPGG----------------------PPGSGIP------- 445

  Fly   447 HPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSA------TTTATPTMQQRIKPL------- 498
               ||.:|...........:.|..|:.:.:.::..:|      |:|:..::..:..|.
Zfish   446 ---GYSLGGRSYPSFSDPTVLAERASRSSSVRSTHNAPPSEATTSTSYKSLANQTPPQAARNGSL 507

  Fly   499 ---GVATP-----LVMASPVRRSNPGTPTQPRRPDFIG-----LNAQAVAQQQQQQQQAAAAAAA 550
               .:.||     ...|:|  ..:||.|..|    .:|     |:||...|::.:..|..|:::|
Zfish   508 SYDSLLTPSESPDFESAAP--EMSPGRPRTP----VVGYSSPFLSAQIAHQREAELHQPVASSSA 566

  Fly   551 -------AYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHA 608
                   |.:...||.||..|     ::::::||...|   .||....               |.
Zfish   567 LMASPQHAVFLRGSGSPPVPP-----ERERERLLHDSQ---AQHHHHH---------------HH 608

  Fly   609 AHPQHAALAQAAYGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGSPQRGVY 673
            .|..|          .|.|                       ::|.....|     :|.||.. |
Zfish   609 HHHHH----------RPPR-----------------------FSRPPLLSD-----SGPPQPS-Y 634

  Fly   674 MWKDTSPGFTNNAGQQQQQQQQAQQVVSSGIGSSAGTLSSSGAAAGVMPH-----AQYMTAGGGA 733
            .::..|...|:.........          :|.|   ||.|.|||..|.:     |....||||
Zfish   635 PYRTRSTDTTHPPRSPHPPP----------LGKS---LSYSSAAAAEMQYRLVRKASASVAGGG- 685

  Fly   734 HPLIMTHSRLQDYTIQQQQQQQQQQAAAAAAASYHRSN--------PTSPTTMPQVS-GAGQSYI 789
                          ||..:.:.|.:       ||.|:|        |:|||....|| ..||::
Zfish   686 --------------IQAPKDEIQMK-------SYSRTNGQPKPSSTPSSPTHPISVSTRPGQAH- 728

  Fly   790 LRYGGGGAVGAAGSSGSLASVTAS--NPATGGGG 821
                     .:||||.|.|.....  ...||.||
Zfish   729 ---------SSAGSSQSPAHKPGGGVKKVTGVGG 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	71/119 (60%)
zdhhc5a	XP_005160301.1	DHHC	116..241	CDD:396215	74/124 (60%)