Protein Alignment Zdhhc8 and ZDHHC4

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001358221.1
• Gene: ZDHHC4 / 55146
• HGNCID: 18471
• Length: 359
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 87/320 - (27%)
• Similarity: 133/320 - (41%)
• Gaps: 84/320 - (26%)

  Fly    14 TFAWIVLLLT-------TFLFFFYPCQFYVKSHPWVLAY--QGVITFFVLANFTLATFMDPGIIP 69
            ||..:.|:|.       |:..|.|..:..:..|..:|.|  .||..||    |||....:||||.
Human    67 TFIVLHLVLQGMVYTEYTWEVFGYCQELELSLHYLLLPYLLLGVNLFF----FTLTCGTNPGIIT 127

  Fly    70 KASPDEDCEEELRAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCS---------------VCN 119
            ||:      |.|...:|:..|:  :..|...|.||...:|.|..|||               |||
Human   128 KAN------ELLFLHVYEFDEV--MFPKNVRCSTCDLRKPARSKHCSECGSRDSSGTSNSTCVCN 184

  Fly   120 HCIETFDHHCPWVNNCIGRRNYRFFFFFLVSL--SIHMLSIFSLCLVYVLKIMP----------- 171
            .|:..|||||.|||||||..|.|:|..::::|  |...::|.|...:..|.:|.
Human   185 WCVHRFDHHCVWVNNCIGAWNIRYFLIYVLTLTASAATVAIVSTTFLVHLVVMSDLYQETYIDDL 249

  Fly   172 ---NIKDTAPIV---------AIILMGLVTILAIPIFGLTGFHMVLVSRGRTTNEQVTGKFKGGY 224
               ::.||..::         .:.::|.|.:|:..:.|...|.:.|.:..:||||
Human   250 GHLHVMDTVFLIQYLFLTFPRIVFMLGFVVVLSFLLGGYLLFVLYLAATNQTTNE---------- 304

  Fly   225 NPFSRGCWHNCCYTQFGP--QYPSLLNPKKYAS-----RRSQVQNQAISTI-CNDRSGQQ 276
              :.||.|..|   |..|  .:|....|:.:.:     .||.:|...:... |::|..|:
Human   305 --WYRGDWAWC---QRCPLVAWPPSAEPQVHRNIHSHGLRSNLQEIFLPAFPCHERKKQE 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	45/159 (28%)
ZDHHC4	NP_001358221.1	DHHC	151..307	CDD:396215	45/167 (27%)