Protein Alignment Zdhhc8 and ZDHHC3

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_047304216.1
• Gene: ZDHHC3 / 51304
• HGNCID: 18470
• Length: 412
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 85/377 - (22%)
• Similarity: 130/377 - (34%)
• Gaps: 131/377 - (34%)

  Fly    13 ATFAWIVLLLTTFLFFF---YPCQFYVKSHPWVLAYQGVI----TFFVLANFTLATFMDP----- 65
            |...|.::|...|:..|   .|.:.||.|     ...|::    .|..||:...|...||
Human    48 AIVTWFLVLYAEFVVLFVMLIPSRDYVYS-----IINGIVFNLLAFLALASHCRAMLTDPVRTCT 107

  Fly    66 -----------------------------GIIPKASPDEDCEEELRAP----LYKNAEINGITVK 97
                                         |.:||.:..::..|.|:..    :||
Human   108 EMAFTLLGRGASFPEKLDKPVSGRSKCLLGAVPKGNATKEFIESLQLKPGQVVYK---------- 162

  Fly    98 MKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLC 162
               |..|...:|.|..|||||..||...||||||||||:|..|.::|..|  ::.|.::|:.:|.
Human   163 ---CPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLF--TMYIALISLHALI 222

  Fly   163 LV--------------YVL--------------KIMP-NIKDT-----APIVAIILM------GL 187
            :|              |.|              |:.| |...|     :|...:||:      ||
Human   223 MVGFHFLHCFEEDWTTYGLNREEMAETGISLHEKMQPLNFSSTECSSFSPPTTVILLILLCFEGL 287

  Fly   188 VTILAIPIFGLTGFHMVLVSRGRTTNEQV-TGKFKGGYNPFSRGC-------WHNCCYTQFGPQY 244
            :.::...:...|..|.:.....:...:|. ..:.||    ...||       | .|.|..:...:
Human   288 LFLIFTSVMFGTQVHSICTDETKRWRKQCPQWRVKG----LCAGCCGPGELAW-PCLYLLWASPH 347

  Fly   245 PSLLNPKKY--ASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGG 294
            |:.|:...:  .||..:..::|..|           .....|.:|..|||.|
Human   348 PNTLSVAWWLSCSRHPEAGHRAPQT-----------KEPAQGAHGELAVSKG 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	43/160 (27%)
ZDHHC3	XP_047304216.1	DHHC	162..309	CDD:396215	43/161 (27%)