Protein Alignment Zdhhc8 and Zdhhc14

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001034432.1
• Gene: Zdhhc14 / 499014
• RGDID: 1565877
• Length: 489
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 144/481 - (29%)
• Similarity: 218/481 - (45%)
• Gaps: 108/481 - (22%)

  Fly    18 IVLLLTTFLFFFYPCQFYV-KSHPWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDE--DCEE 79
            |::|:|:.|||.:.|::.. |..|.:....|::.|||:......:|.|||::|:|:|||  |.|.
  Rat    69 ILILVTSGLFFAFDCRYLAEKITPAIPVVGGILFFFVMGTLLRTSFSDPGVLPRATPDEAADLER 133

  Fly    80 EL------------RAPLYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWV 132
            ::            ..|..|...|||.|||:|:|.|||.:||||.||||:|::|:|.||||||||
  Rat   134 QIDIANGTSSGGYRPPPRTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVEQFDHHCPWV 198

  Fly   133 NNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLK------IMPNIKDTAPIVAIILMGLVTIL 191
            .||:|:||||||:.|::|||...:.||:..:.:|:.      .:..:||:.   |.:|..::...
  Rat   199 GNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHVIHRSQQKGFLDALKDSP---ASVLEAVICFF 260

  Fly   192 AI-PIFGLTGFHMVLVSRGRTTNEQVTGKF-----KGGYNPFSRG-CWHNCCYTQFGPQYPSLLN 249
            :: .|.||:|||..|:|..:||||.:.|.:     |..|||:|.| .:.|||....||..|||::
  Rat   261 SVWSIIGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLID 325

  Fly   250 PKKYASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPR 314
                  ||..:|...          .|..|.|                       .|..:..:.:
  Rat   326 ------RRGYIQPDT----------PQPAAPS-----------------------NGITMYGATQ 351

  Fly   315 SFYDASREKRGIQVKTYM--AEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPPPASQSQDCEPTP 377
            |..|...:.:.||...::  |......|...|.|......||:    ..|..|.||.:.. :|||
  Rat   352 SQSDMCDQDQCIQSTKFVLQAAATPLLQSEPSLTSEELHMPGK----PGLGTPCASLTLG-QPTP 411

  Fly   378 PLQRHNSSSFYLPQVSDSGGLNGSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDA 442
            |      ||  :|.::....|:..:                  |....|...:.|.|     .:|
  Rat   412 P------SS--MPNLATEATLSDIM------------------PLKDEHGGHQFLTP-----DEA 445

  Fly   443 LSPDHPVGYGVGVNGSQQQQQQALAA 468
            .||...:|.|..:..|:......||:
  Rat   446 PSPPRMLGAGSPLAHSRTMHMLGLAS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	56/126 (44%)
Zdhhc14	NP_001034432.1	DHHC	164..287	CDD:396215	56/125 (45%)
		Atrophin-1	351..>461	CDD:460830	31/145 (21%)