Protein Alignment Zdhhc8 and app

DIOPT Version :10

• Sequence 1: NP_001259382.1
• Gene: Zdhhc8 / 31887
• FlyBaseID: FBgn0085478
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 782
• Identity: 222/782 - (28%)
• Similarity: 317/782 - (40%)
• Gaps: 196/782 - (25%)

  Fly     4 CDVKTRYIPAT----FAWIVLLLTTFLFFFYPCQFYVKS-HPWVLAYQGVITFFVLANFTLATFM 63
            ||......|.|    ...|::..|:.|||.:.|.|...| :|.:.....|:.||.:::....||.
  Fly    33 CDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINPAIPIVGAVLYFFTMSSLLRTTFT 97

  Fly    64 DPGIIPKASPDE--------DCEEELRAPLY------KNAEINGITVKMKWCVTCKFYRPPRCSH 114
            |||:||:||.||        :....|.:|.|      |...:.|.|||:|:|.|||.:||||.||
  Fly    98 DPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLVKGQTVKLKYCFTCKIFRPPRASH 162

  Fly   115 CSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMP------NI 173
            ||:|::|::.||||||||.||:|:||||||:.|||||:...:.|||..:.:::.:|.      |:
  Fly   163 CSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAVFIFSCSVTHLVLLMKKEHEVFNV 227

  Fly   174 KDTAPIVAIILMGLVTILAI-PIFGLTGFHMVLVSRGRTTNEQVTGKF--KGG---YNPFSRG-- 230
            ...||...|::  .:...:| .:.||.|||..|.:..:||||.:.|.|  |||   .||:|||
  Fly   228 IKAAPFTVIVV--FICFFSIWSVIGLAGFHTYLTTSDQTTNEDLKGSFSSKGGPRTQNPYSRGNI 290

  Fly   231 CWHNCCYTQFGPQYPSLLNPKKYASRR--SQVQNQ-----AISTICNDRSGQQTGAGSGAGGNGT 288
            |. |||:...||..|||::.:..|:..  .|:|:|     |:|.:.: .|...|.:....||.|.
  Fly   291 CL-NCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALSDVLS-ASHMVTTSQPMMGGLGG 353

  Fly   289 AAVSGGGGGVGSGGGMRGTAVQYSPRSFYDASR------EKRGIQVKTY-MAEGNGYNQRSGSTT 346
            ..:.|.|||:..||      .:..|| |||.|.      |..|..:..: ...|||::....|..
  Fly   354 GGIGGAGGGISIGG------AELKPR-FYDESNPSSSTLEGNGGAINGHGNGHGNGFDHPPPSYD 411

  Fly   347 LY----SKLSPGRECSDTDLEPPPASQSQDCEPTPPLQRHNSSSFYLPQVSDSGGLNGSVSTGGG 407
            |.    |:....:.||...|  .|||..|..:.:....:.........::....|       |.|
  Fly   412 LVQNGKSRKHHQQRCSLQTL--LPASAQQQFKASKHKHKQLKQHLVAAELQQHEG-------GPG 467

  Fly   408 GGGDSPRHMR-----------LYHPRHSPHARPRGLDPQRGYTSDALSP----DHPVGYGVGVNG 457
            .|.:||..:|           |....|.|      |.|  .|.....||    .|.|
  Fly   468 PGPNSPSLLRSPATSSSYRLNLKRSLHLP------LTP--SYDDVRHSPLPLLHHHV-------- 516

  Fly   458 SQQQQQQALAAAAAAAAVAAQ---------------NQRSATTTATPTMQQRIKPLGVATPLVMA 507
             ..||..|:...|||||..|.               :..||||||         |..|:..|..|
  Fly   517 -HAQQTTAIGTVAAAAAAVASGASGTNTGTGTGTGGSSSSATTTA---------PTSVSVSLATA 571

  Fly   508 SPVRRSNPGTPTQPRRPDFIGLNAQAVAQQQQQ-----QQQAAAAAAAAYYEYTSGLPPQH---- 563
            .|        |..||||..:.|.|.........     ...|..|.|...::|.|   ||.
  Fly   572 PP--------PLAPRRPSTLQLQASGAISASNSTLTTIHTTAPQAPAPTDFKYYS---PQRSTDS 625

  Fly   564 --------PQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHAAHPQHAALAQAA 620
                    |:|....::|..:.:..|:|.:...|.....:..:.|:....:.
  Fly   626 NLMRNYPFPKAARGMRRQSTMSVDSQKVNIAGYQPLPMRKPYKHQEVMFELK------------- 677

  Fly   621 YGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGS-----PQRGVYM-----W 675
               ||..|.     .:|:...||  |||        ..|:.:.:..|     .:|.:||     |
  Fly   678 ---SPTNRL-----TIRECDFGG--GGE--------PCDDDQSIKDSQIFRVSKRNLYMNHRSPW 724

  Fly   676 KD 677
            |:
  Fly   725 KE 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	DHHC	99..219	CDD:396215	56/126 (44%)
app	NP_648561.2	DHHC	146..270	CDD:396215	56/125 (45%)