DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_001259382.1	Gene:	Zdhhc8 / 31887	FlyBaseID:	FBgn0085478	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	212	Identity:	56/212 - (26%)
Similarity:	80/212 - (37%)	Gaps:	55/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 KASPDEDCEEELRAPLYKNAEINGIT---------VKMKWCVTCKFYRPPRCSHCSVCNHCIETF 125
            |..|..|....|.....|: ::.|.:         ||..||..|:..||.|..||.:|..|:...
Mouse   212 KGFPGTDASGSLNNRTLKD-DVRGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRM 275

  Fly   126 DHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPN--IKDTAPIVA------- 181
            ||||.|:|:|:|..|::.|        |..||||.|..||.:.:..|  .:|.:...|
Mouse   276 DHHCVWINSCVGESNHQAF--------ILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCPGV 332

  Fly   182 -----------------IILMGLVTILAIPI----FGLTGFHMVLVSRGRTTNEQVTGKF--KGG 223
                             ||..|:..|..|.:    :.:|...:....|.:|....:.|..  .|.
Mouse   333 YANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTGQ 397

  Fly   224 YNPFSRGCWHNCCYTQF 240
            ||   ||...|  :.||
Mouse   398 YN---RGFLRN--WLQF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001259382.1	zf-DHHC	94..219	CDD:279823	41/163 (25%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	37/133 (28%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900